Literature DB >> 16267708

[Splenosis--important differential diagnosis in splenectomized patients presenting with abdominal masses of unknown origin].

J Wedemeyer1, K F Gratz, B Soudah, H Rosenthal, C Strassburg, C Terkamp, M J Bahr, M P Manns, M J Gebel, J S Bleck.   

Abstract

A 40-year-old female patient was admitted for work-up of multiple abdominal masses. The lymphoma-mimicking tumors were detected accidentally during an ultrasound course. The past medical history was unremarkable besides a status post-traumatic splenic rupture and splenectomy. The patient was asymptomatic, especially there were no complaints of fever, night sweats or weight loss. Laboratory tests did not show pathological results. Ultrasound of the abdomen revealed multiple hypoechoic mesenterial and peritoneal enlarged tumors as well as a subhepatic mass (30 x 20 mm). Transmission computed tomography (CT) showed a normal chest, excluded abnormal thoracal masses and confirmed the multiple abdominal nodules. Microparticles were trapped only by tissue with phagocytosis function as cells of the reticulohistiocytary system in liver and spleen. Uptake of (99 m)Tc-labeled microparticles is specific for splenic tissue. All abdominal masses were detectable by single photon emission computed tomography (SPECT) after intravenous administration of this radiotracer. Ultrasound-guided biopsy proved the presence of spleen tissue with follicular hyperplasia. In conclusion, we report a case of post-traumatic splenosis. In 16 - 67 % of patients who experienced traumatic splenic rupture autotransplanted spleen tissue can be detected. Splenosis therefore is an important differential diagnosis of abdominal masses in splenectomized patients.

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Year:  2005        PMID: 16267708     DOI: 10.1055/s-2005-858640

Source DB:  PubMed          Journal:  Z Gastroenterol        ISSN: 0044-2771            Impact factor:   2.000


  2 in total

1.  Splenosis: 99mTc-labelled colloids provide the diagnosis in splenectomised patients.

Authors:  Antonella Franceschetto; Alessandra Casolo; Marina Cucca; Bruno Bagni
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-06-09       Impact factor: 9.236

2.  Splenosis involving the gastric fundus, a rare cause of massive upper gastrointestinal bleeding: a case report and review of the literature.

Authors:  Jason Reinglas; Kirstin Perdrizet; Stephen E Ryan; Rakesh V Patel
Journal:  Clin Exp Gastroenterol       Date:  2016-09-22
  2 in total

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