Literature DB >> 1626652

Alcohol withdrawal in rats is associated with a marked fall in extraneuronal dopamine.

Z L Rossetti1, F Melis, S Carboni, M Diana, G L Gessa.   

Abstract

Withdrawal of rats from chronic ethanol (2-5 g/kg, every 6 hr for 6 days) resulted in withdrawal symptomatology and dramatic fall in extracellular dopamine (DA) in the ventral striatum as measured by microdialysis. The changes in DA output paralleled the withdrawal symptomatology and both phenomena were reversed by a challenge ethanol dose (5 g/kg orally). The results suggest that the decrease in DA output may be responsible for the aversive symptoms of withdrawal.

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Year:  1992        PMID： 1626652     DOI： 10.1111/j.1530-0277.1992.tb01411.x

Source DB:  PubMed          Journal:  Alcohol Clin Exp Res        ISSN： 0145-6008            Impact factor:   3.455


  28 in total

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2.  Adolescent intermittent ethanol exposure diminishes anhedonia during ethanol withdrawal in adulthood.

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5.  Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats.

Authors:  F Weiss; L H Parsons; G Schulteis; P Hyytiä; M T Lorang; F E Bloom; G F Koob
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6.  Evidence for prolonged recovery of dopaminergic transmission after detoxification in alcoholics with poor treatment outcome.

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Journal:  Psychopharmacology (Berl)       Date:  2016-02-19       Impact factor: 4.530

Review 8.  Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure.

Authors:  Cody A Siciliano; Anushree N Karkhanis; Katherine M Holleran; James R Melchior; Sara R Jones
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9.  GDNF and alcohol use disorder.

Authors:  Segev Barak; Somayeh Ahmadiantehrani; Marian L Logrip; Dorit Ron
Journal:  Addict Biol       Date:  2018-05-04       Impact factor: 4.280

Review 10.  Amygdalostriatal projections in the neurocircuitry for motivation: a neuroanatomical thread through the career of Ann Kelley.

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Journal:  Neurosci Biobehav Rev       Date:  2012-12-07       Impact factor: 8.989
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