Robert Rapaport1, Torsten Tuvemo. 1. Division of Pediatric Endocrinology and Diabetes, Mount Sinai School of Medicine, New York, NY 10029-5216, USA. robert.rapaport@msnyuhealth.org
Abstract
UNLABELLED: Although most children born small for gestational age catch up in growth by age 2 y, up to 14% remain more than 2 standard deviations below the mean for height. Recombinant growth hormone is approved by the US Food and Drug Administration and by the European Agency for Evaluation of Medicinal Products for the treatment of children born small for gestational age who fail to manifest catch-up growth by 2 y or 4 y, respectively. CONCLUSION: We conclude from clinical studies that growth hormone therapy can induce catch-up growth in these children.
UNLABELLED: Although most children born small for gestational age catch up in growth by age 2 y, up to 14% remain more than 2 standard deviations below the mean for height. Recombinant growth hormone is approved by the US Food and Drug Administration and by the European Agency for Evaluation of Medicinal Products for the treatment of children born small for gestational age who fail to manifest catch-up growth by 2 y or 4 y, respectively. CONCLUSION: We conclude from clinical studies that growth hormone therapy can induce catch-up growth in these children.