| Literature DB >> 1626314 |
Abstract
The response of extracellular norepinephrine to the acute administration of amphetamine was assessed, using dialysis, in prefrontal cortex and hippocampus in awake, behaving rats. Norepinephrine exhibited a pronounced and rapid dose- and time-dependent increase in response to 0.5 and 2.5 mg/kg amphetamine, which corresponded closely to the time course of the behavioral profile. These results are consistent in with a possible role for norepinephrine in the behavioral response to amphetamine.Entities:
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Year: 1992 PMID: 1626314 DOI: 10.1002/syn.890110210
Source DB: PubMed Journal: Synapse ISSN: 0887-4476 Impact factor: 2.562