| Literature DB >> 16262557 |
Abstract
Conventional nonselective NSAIDs are classically associated with a risk of gastrointestinal disorders. These drugs have a broad range of relative selectivity towards the COX family, mainly towards two isoforms of these enzymes: COX-1 and -2. As examples, ketorolac, flurbiprofen, ketoprofen and indomethacin have increased COX-1 selectivity when compared with naproxen and ibuprofen.Entities:
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Year: 2005 PMID： 16262557 DOI： 10.1517/14728214.10.4.687
Source DB: PubMed Journal: Expert Opin Emerg Drugs ISSN： 1472-8214 Impact factor: 4.191