Literature DB >> 16261425

Small animal imaging center design: the facility at the UCLA Crump Institute for Molecular Imaging.

David B Stout1, Arion F Chatziioannou, Timothy P Lawson, Robert W Silverman, Sanjiv S Gambhir, Michael E Phelps.   

Abstract

PURPOSE: The growing number of mouse and rat experiments, coupled with advances in small-animal imaging systems such as microPET, optical, microCAT, microMR, ultrasound and microSPECT, has necessitated a common technical center for imaging small animals. PROCEDURES: At the UCLA Crump Institute for Molecular Imaging, we have designed and built a facility to support the research interests of a wide range of investigators from multiple disciplines. Requirements to satisfy both research and regulatory oversight have been critically examined. Support is provided for investigator training, study scheduling, data acquisition, archiving, image display, and analysis.
RESULTS: The center has been in operation for more than 18 months, supporting more than 13,000 individual imaging procedures.
CONCLUSIONS: We have created a facility that maximizes our resource utilization while providing optimal investigator support, as well as the means to continually improve the quality and diversity of the science by integrating physical and biological sciences.

Entities:  

Mesh:

Year:  2005        PMID: 16261425      PMCID: PMC3005624          DOI: 10.1007/s11307-005-0015-2

Source DB:  PubMed          Journal:  Mol Imaging Biol        ISSN: 1536-1632            Impact factor:   3.488


  16 in total

1.  In vivo imaging of light-emitting probes.

Authors:  B W Rice; M D Cable; M B Nelson
Journal:  J Biomed Opt       Date:  2001-10       Impact factor: 3.170

2.  Performance evaluation of the microPET P4: a PET system dedicated to animal imaging.

Authors:  C Tai; A Chatziioannou; S Siegel; J Young; D Newport; R N Goble; R E Nutt; S R Cherry
Journal:  Phys Med Biol       Date:  2001-07       Impact factor: 3.609

Review 3.  High resolution X-ray computed tomography: an emerging tool for small animal cancer research.

Authors:  M J Paulus; S S Gleason; S J Kennel; P R Hunsicker; D K Johnson
Journal:  Neoplasia       Date:  2000 Jan-Apr       Impact factor: 5.715

4.  AMIDE: a free software tool for multimodality medical image analysis.

Authors:  Andreas Markus Loening; Sanjiv Sam Gambhir
Journal:  Mol Imaging       Date:  2003-07       Impact factor: 4.488

Review 5.  In vivo molecular-genetic imaging: multi-modality nuclear and optical combinations.

Authors:  Ronald G Blasberg
Journal:  Nucl Med Biol       Date:  2003-11       Impact factor: 2.408

6.  Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph.

Authors:  Takashi Kudo; Kazuki Fukuchi; Alexander J Annala; Arion F Chatziioannou; Vivekanand Allada; Magnus Dahlbom; Yuan-Chuan Tai; Masayuki Inubushi; Sung-Cheng Huang; Simon R Cherry; Michael E Phelps; Heinrich R Schelbert
Journal:  Circulation       Date:  2002-07-02       Impact factor: 29.690

7.  PET scanners dedicated to molecular imaging of small animal models.

Authors:  Arion F Chatziioannou
Journal:  Mol Imaging Biol       Date:  2002-01       Impact factor: 3.488

8.  Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models.

Authors:  Tamara Troy; Dragana Jekic-McMullen; Lidia Sambucetti; Brad Rice
Journal:  Mol Imaging       Date:  2004-01       Impact factor: 4.488

Review 9.  PET: the merging of biology and imaging into molecular imaging.

Authors:  M E Phelps
Journal:  J Nucl Med       Date:  2000-04       Impact factor: 10.057

10.  Long-term anaesthesia using inhalatory isoflurane in different strains of mice-the haemodynamic effects.

Authors:  Grzegorz Szczesny; Andreas Veihelmann; Steffen Massberg; Dirk Nolte; Konrad Messmer
Journal:  Lab Anim       Date:  2004-01       Impact factor: 2.471

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  19 in total

1.  MIDG-Emerging grid technologies for multi-site preclinical molecular imaging research communities.

Authors:  Jasper Lee; Jorge Documet; Brent Liu; Ryan Park; Archana Tank; H K Huang
Journal:  Int J Comput Assist Radiol Surg       Date:  2010-08-06       Impact factor: 2.924

Review 2.  Emerging imaging techniques.

Authors:  Elliot R McVeigh
Journal:  Circ Res       Date:  2006-04-14       Impact factor: 17.367

3.  A method of image registration for small animal, multi-modality imaging.

Authors:  Patrick L Chow; David B Stout; Evangelia Komisopoulou; Arion F Chatziioannou
Journal:  Phys Med Biol       Date:  2006-01-04       Impact factor: 3.609

4.  Study of an image-derived SUV and a modified SUV using mouse FDG-PET.

Authors:  Xiujuan Zheng; Chin-Lung Yu; Wei Sha; Caius Radu; Sung-Cheng Huang; Dagan Feng
Journal:  Nucl Med Biol       Date:  2010-12-03       Impact factor: 2.408

5.  Mouse atlas registration with non-tomographic imaging modalities-a pilot study based on simulation.

Authors:  Hongkai Wang; David B Stout; Arion F Chatziioannou
Journal:  Mol Imaging Biol       Date:  2012-08       Impact factor: 3.488

6.  Performance evaluation of PETbox: a low cost bench top preclinical PET scanner.

Authors:  Hui Zhang; Qinan Bao; Nam T Vu; Robert W Silverman; Richard Taschereau; Brittany N Berry-Pusey; Ali Douraghy; Fernando R Rannou; David B Stout; Arion F Chatziioannou
Journal:  Mol Imaging Biol       Date:  2011-10       Impact factor: 3.488

7.  MicroCT liver contrast agent enhancement over time, dose, and mouse strain.

Authors:  Chris E Suckow; David B Stout
Journal:  Mol Imaging Biol       Date:  2008-01-16       Impact factor: 3.488

8.  Multimodality rodent imaging chambers for use under barrier conditions with gas anesthesia.

Authors:  Chris Suckow; Claudia Kuntner; Patrick Chow; Robert Silverman; Arion Chatziioannou; David Stout
Journal:  Mol Imaging Biol       Date:  2008-08-05       Impact factor: 3.488

9.  MARS: a mouse atlas registration system based on a planar x-ray projector and an optical camera.

Authors:  Hongkai Wang; David B Stout; Richard Taschereau; Zheng Gu; Nam T Vu; David L Prout; Arion F Chatziioannou
Journal:  Phys Med Biol       Date:  2012-09-12       Impact factor: 3.609

10.  Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress.

Authors:  Jesus A Araujo; Andre E Nel
Journal:  Part Fibre Toxicol       Date:  2009-09-18       Impact factor: 9.400

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