Literature DB >> 16261239

The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids.

Biswadip Banerji1, Ana Conejo-Garcia, Luke A McNeill, Michael A McDonough, Matthew R G Buck, Kirsty S Hewitson, Neil J Oldham, Christopher J Schofield.   

Abstract

Cyclic beta-oxocarboxylic acids inhibit factor inhibiting hypoxia-inducible factor via ligation to the active site iron.

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Year:  2005        PMID: 16261239     DOI: 10.1039/b510707e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  15 in total

1.  Supramolecular Polymer Hydrogels for Drug-Induced Tissue Regeneration.

Authors:  Jing Cheng; Devang Amin; Jessica Latona; Ellen Heber-Katz; Phillip B Messersmith
Journal:  ACS Nano       Date:  2019-05-14       Impact factor: 15.881

2.  Drug-induced regeneration in adult mice.

Authors:  Yong Zhang; Iossif Strehin; Khamilia Bedelbaeva; Dmitri Gourevitch; Lise Clark; John Leferovich; Phillip B Messersmith; Ellen Heber-Katz
Journal:  Sci Transl Med       Date:  2015-06-03       Impact factor: 17.956

3.  The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.

Authors:  Na Zhang; Zhenxing Fu; Sarah Linke; Johana Chicher; Jeffrey J Gorman; DeeAnn Visk; Gabriel G Haddad; Lorenz Poellinger; Daniel J Peet; Frank Powell; Randall S Johnson
Journal:  Cell Metab       Date:  2010-04-15       Impact factor: 27.287

4.  Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH).

Authors:  Shannon C Flagg; Cristina B Martin; Cornelius Y Taabazuing; Breanne E Holmes; Michael J Knapp
Journal:  J Inorg Biochem       Date:  2012-03-17       Impact factor: 4.155

Review 5.  In situ forming injectable hydrogels for drug delivery and wound repair.

Authors:  Robert Dimatteo; Nicole J Darling; Tatiana Segura
Journal:  Adv Drug Deliv Rev       Date:  2018-03-19       Impact factor: 15.470

Review 6.  Oxygen sensing strategies in mammals and bacteria.

Authors:  Cornelius Y Taabazuing; John A Hangasky; Michael J Knapp
Journal:  J Inorg Biochem       Date:  2014-01-03       Impact factor: 4.155

Review 7.  Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.

Authors:  John A Hangasky; Cornelius Y Taabazuing; Meaghan A Valliere; Michael J Knapp
Journal:  Metallomics       Date:  2013-04       Impact factor: 4.526

8.  Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).

Authors:  Vanessa D Chaplin; Meaghan A Valliere; John A Hangasky; Michael J Knapp
Journal:  J Inorg Biochem       Date:  2017-10-07       Impact factor: 4.155

9.  An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis.

Authors:  Kosuke Nagai; Hidetaka Ideguchi; Tetsuhiro Kajikawa; Xiaofei Li; Triantafyllos Chavakis; Jing Cheng; Phillip B Messersmith; Ellen Heber-Katz; George Hajishengallis
Journal:  FASEB J       Date:  2020-08-19       Impact factor: 5.191

10.  Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).

Authors:  Michael A McDonough; Vivian Li; Emily Flashman; Rasheduzzaman Chowdhury; Christopher Mohr; Benoît M R Liénard; James Zondlo; Neil J Oldham; Ian J Clifton; Jeffrey Lewis; Luke A McNeill; Robert J M Kurzeja; Kirsty S Hewitson; Evelyn Yang; Steven Jordan; Rashid S Syed; Christopher J Schofield
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-16       Impact factor: 11.205

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