Literature DB >> 16261178

Neuroenergetics and the kinetic design of excitatory synapses.

David Attwell1, Alasdair Gibb.   

Abstract

Why is the characteristic timescale of neural information processing in the millisecond range, corresponding to a 'clock speed' of about 1 kHz, whereas the clock speed of modern computers is about 3 GHz? Here we investigate how the brain's energy supply limits the maximum rate at which the brain can compute, and how the molecular components of excitatory synapses have evolved properties that are matched to the information processing they perform.

Mesh:

Year:  2005        PMID: 16261178     DOI: 10.1038/nrn1784

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  69 in total

Review 1.  Reactive Oxygen Species: the Dual Role in Physiological and Pathological Conditions of the Human Body.

Authors:  Sanaa K Bardaweel; Mustafa Gul; Muhammad Alzweiri; Aman Ishaqat; Husam A ALSalamat; Rasha M Bashatwah
Journal:  Eurasian J Med       Date:  2018-10

2.  Delta oscillations induced by ketamine increase energy levels in sleep-wake related brain regions.

Authors:  M Dworak; R W McCarley; T Kim; R Basheer
Journal:  Neuroscience       Date:  2011-09-17       Impact factor: 3.590

3.  Counting on dis-inhibition: a circuit motif for interval counting and selectivity in the anuran auditory system.

Authors:  Richard Naud; Dave Houtman; Gary J Rose; André Longtin
Journal:  J Neurophysiol       Date:  2015-09-02       Impact factor: 2.714

4.  Amelioration of ischemic brain damage by peritoneal dialysis.

Authors:  María del Carmen Godino; Victor G Romera; José Antonio Sánchez-Tomero; Jesus Pacheco; Santiago Canals; Juan Lerma; José Vivancos; María Angeles Moro; Magdalena Torres; Ignacio Lizasoain; José Sánchez-Prieto
Journal:  J Clin Invest       Date:  2013-09-03       Impact factor: 14.808

5.  How much the eye tells the brain.

Authors:  Kristin Koch; Judith McLean; Ronen Segev; Michael A Freed; Michael J Berry; Vijay Balasubramanian; Peter Sterling
Journal:  Curr Biol       Date:  2006-07-25       Impact factor: 10.834

6.  Tonic activation of NMDA receptors by ambient glutamate of non-synaptic origin in the rat hippocampus.

Authors:  Karim Le Meur; Micaela Galante; María Cecilia Angulo; Etienne Audinat
Journal:  J Physiol       Date:  2006-12-21       Impact factor: 5.182

7.  Impaired Energy Metabolism and Disturbed Dopamine and Glutamate Signalling in the Striatum and Prefrontal Cortex of the Spontaneously Hypertensive Rat Model of Attention-Deficit Hyperactivity Disorder.

Authors:  Jacqueline J Dimatelis; Jennifer H Hsieh; Toni-Lee Sterley; Lelanie Marais; Jacqueline S Womersley; Maré Vlok; Vivienne A Russell
Journal:  J Mol Neurosci       Date:  2015-02-11       Impact factor: 3.444

Review 8.  Inhibition and brain work.

Authors:  György Buzsáki; Kai Kaila; Marcus Raichle
Journal:  Neuron       Date:  2007-12-06       Impact factor: 17.173

9.  On-site energy supply at synapses through monocarboxylate transporters maintains excitatory synaptic transmission.

Authors:  Masashi Nagase; Yukari Takahashi; Ayako M Watabe; Yoshihiro Kubo; Fusao Kato
Journal:  J Neurosci       Date:  2014-02-12       Impact factor: 6.167

10.  Energy metabolism of the visual system.

Authors:  Margaret T T Wong-Riley
Journal:  Eye Brain       Date:  2010-07-22
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