Literature DB >> 16261172

Opinion: antibody-based therapies for malaria.

Richard J Pleass1, Anthony A Holder.   

Abstract

Antibodies are multifunctional glycoproteins that are found in blood and tissue fluids, and can protect against malaria by binding and neutralizing malaria parasites and preparing them for destruction by immune cells. Important technical advances mean that it is now possible to synthesize antibodies against important Plasmodium antigens that could be used for therapeutic purposes. These reagents could be designed to act like a drug and kill parasites directly, or could be used in vaccine strategies to protect individuals from infection. In this article, we discuss the possible therapeutic uses of antibodies in the treatment and prevention of malaria.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16261172     DOI： 10.1038/nrmicro1267

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN： 1740-1526            Impact factor:   60.633


  15 in total

Review 1.  Approaches to malaria vaccine development using the retrospectroscope.

Authors:  Vanessa Sardá; David C Kaslow; Kim C Williamson
Journal:  Infect Immun       Date:  2009-05-18       Impact factor: 3.441

2.  Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region.

Authors:  Justin Doritchamou; Andrew Teo; Robert Morrison; Gunjan Arora; Jennifer Kwan; Javier Manzella-Lapeira; Sarimar Medina-Maldonado; Jean Langhorne; Lars Hviid; David L Narum; Alassane Dicko; Michal Fried; Patrick E Duffy
Journal:  Infect Immun       Date:  2019-06-20       Impact factor: 3.441

3.  Suppressive and additive effects in protection mediated by combinations of monoclonal antibodies specific for merozoite surface protein 1 of Plasmodium yoelii.

Authors:  Irosoki Eslava; Gilberto Payares; Beatriz M Pernia; Anthony A Holder; Lilian M Spencer
Journal:  Malar J       Date:  2010-02-10       Impact factor: 2.979

Review 4.  Fc-receptors and immunity to malaria: from models to vaccines.

Authors:  R J Pleass
Journal:  Parasite Immunol       Date:  2009-09       Impact factor: 2.280

5.  Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.

Authors:  Maria Lazarou; José A Guevara Patiño; Richard M Jennings; Richard S McIntosh; Jianguo Shi; Steven Howell; Eilish Cullen; Tarran Jones; Jaime R Adame-Gallegos; Jonathan A Chappel; Jana S McBride; Michael J Blackman; Anthony A Holder; Richard J Pleass
Journal:  Infect Immun       Date:  2009-10-05       Impact factor: 3.441

Review 6.  Using two phases of the CD4 T cell response to blood-stage murine malaria to understand regulation of systemic immunity and placental pathology in Plasmodium falciparum infection.

Authors:  Komi Gbedande; Victor H Carpio; Robin Stephens
Journal:  Immunol Rev       Date:  2020-01       Impact factor: 12.988

Review 7.  Antibodies against Plasmodium falciparum malaria at the molecular level.

Authors:  Jean-Philippe Julien; Hedda Wardemann
Journal:  Nat Rev Immunol       Date:  2019-08-28       Impact factor: 53.106

8.  The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).

Authors:  Jianguo Shi; Richard S McIntosh; Jaime Adame-Gallegos; Prabhjyot K Dehal; Marjolein van Egmond; Jan van de Winkel; Simon J Draper; Emily K Forbes; Patrick H Corran; Anthony A Holder; Jenny M Woof; Richard J Pleass
Journal:  BMC Biotechnol       Date:  2011-07-22       Impact factor: 2.563

9.  Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody.

Authors:  Stephanie Kapelski; Alexander Boes; Holger Spiegel; Melanie de Almeida; Torsten Klockenbring; Andreas Reimann; Rainer Fischer; Stefan Barth; Rolf Fendel
Journal:  Malar J       Date:  2015-02-05       Impact factor: 2.979

10.  The importance of human FcgammaRI in mediating protection to malaria.

Authors:  Richard S McIntosh; Jianguo Shi; Richard M Jennings; Jonathan C Chappel; Tania F de Koning-Ward; Tim Smith; Judith Green; Marjolein van Egmond; Jeanette H W Leusen; Maria Lazarou; Jan van de Winkel; Tarran S Jones; Brendan S Crabb; Anthony A Holder; Richard J Pleass
Journal:  PLoS Pathog       Date:  2007-05-18       Impact factor: 6.823
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.