Literature DB >> 16261120

An outcomes analysis of the treatment of cervical pseudarthrosis with posterior fusion.

Craig A Kuhns1, Matthew J Geck, Jeffrey C Wang, Rick B Delamarter.   

Abstract

STUDY
DESIGN: A retrospective review of 33 consecutive patients treated with posterior fusion and selective nerve root decompression for the treatment of pseudarthrosis following anterior cervical discectomy and fusion.
OBJECTIVES: Use standardized outcome measures to evaluate the results of posterior fusion with selective nerve root decompression as a treatment option for symptomatic pseudarthrosis of the cervical spine. SUMMARY OF BACKGROUND DATA: Pseudarthrosis after anterior cervical discectomy and fusion has been recognized as a cause of continued cervical pain and unsatisfactory outcomes. Debate continues as to whether a revision anterior approach or a posterior fusion procedure is the best treatment for symptomatic cervical pseudarthrosis. To our knowledge, standardized outcome measures have not been used to evaluate the results of either surgical treatment option; therefore, it is difficult to evaluate outcomes in these patients, let alone compare surgical treatment options. Data on fusion rates in these two surgical treatment groups suggest a trend of a higher fusion rate with utilization of a posterior revision procedure, but the largest study to date includes the study of only 19 patients treated with a posterior fusion.
METHODS: Thirty-three consecutive patients with symptomatic pseudarthrosis following anterior cervical discectomy and fusion were treated with selective nerve root decompression and posterior fusion using iliac crest or local bone graft as well as posterior wiring and/or lateral mass plating. The average follow-up period was 46 months (range, 20-86 months). Patients were assessed using physical examination, flexion-extension lateral radiographs, and standardized outcome measures including the SF-36, Arthritis Impact Measurement Scales 2, and Cervical Spine Outcomes Questionnaire.
RESULTS: All 33 patients (100%) demonstrated a solid fusion at their most recent follow-up, and all 33 patients noted significant improvement in their preoperative symptoms. No difference in fusion status was noted between those treated with iliac crest versus patients treated with local bone graft--all had a solid fusion; 72% of the patients were satisfied with the result of their surgery. Cervical Spine Outcomes Questionnaire pain scales demonstrated 52% of patients reported mild or nopain at follow-up, whereas 20% described their pain as "discomforting" and 28% of the patients continued to report moderate to severe pain.
CONCLUSIONS: This is the first study to our knowledge to use standardized outcome measures to assess clinical outcome in patients treated with posterior fusion for pseudarthrosis after anterior cervical discectomy and fusion. Patients and surgeons need to understand the potential for success with this revision procedure but also be aware of the relatively high rate of continued moderate to severe pain observed in this patient population even after a solid fusion is achieved. All of the patients in this study fused with a single posterior fusion procedure, further supporting the relatively higher fusion rates observed in the literature using posterior fusion as a treatment for cervical pseudarthrosis. Our results also support the ability of surgeons to use local bone graft without iliac crest in a posterior fusion for cervical pseudarthrosis and therefore avoid the morbidity associated with iliac crest bone graft harvest.

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Mesh:

Year:  2005        PMID: 16261120     DOI: 10.1097/01.brs.0000184314.26543.7d

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  10 in total

1.  Does smoking influence fusion rates in posterior cervical arthrodesis with lateral mass instrumentation?

Authors:  Jason David Eubanks; Steven W Thorpe; Vinay K Cheruvu; Brett A Braly; James D Kang
Journal:  Clin Orthop Relat Res       Date:  2011-03       Impact factor: 4.176

Review 2.  Revision surgery for failed cervical spine reconstruction: review article.

Authors:  John D Koerner; Christopher K Kepler; Todd J Albert
Journal:  HSS J       Date:  2014-07-25

3.  Outcomes of Revision Surgery for Pseudarthrosis After Anterior Cervical Fusion: Case Series and Systematic Review.

Authors:  Michael E Steinhaus; Philip J York; Rachel S Bronheim; Jingyan Yang; Francis Lovecchio; Han Jo Kim
Journal:  Global Spine J       Date:  2019-08-01

Review 4.  Failure in Cervical Spinal Fusion and Current Management Modalities.

Authors:  Terence Verla; David S Xu; Matthew J Davis; Edward M Reece; Michelle Kelly; Mervin Nunez; Sebastian J Winocour; Alexander E Ropper
Journal:  Semin Plast Surg       Date:  2021-05-10       Impact factor: 2.314

Review 5.  A Meta-Analysis of the Clinical and Fusion Results following Treatment of Symptomatic Cervical Pseudarthrosis.

Authors:  Steven J McAnany; Evan O Baird; Samuel C Overley; Jun S Kim; Sheeraz A Qureshi; Paul A Anderson
Journal:  Global Spine J       Date:  2015-01-30

6.  Analysis of postoperative pain at the anterior iliac crest harvest site: a prospective study of the intraoperative local administration of ropivacaine.

Authors:  Juliane Zenner; Wolfgang Hitzl; Michael Mayer; Heiko Koller
Journal:  Asian Spine J       Date:  2015-02-13

Review 7.  Pseudarthrosis of the Cervical Spine: Risk Factors, Diagnosis and Management.

Authors:  Dante Leven; Samuel K Cho
Journal:  Asian Spine J       Date:  2016-08-16

8.  Trends and Cost of Posterior Cervical Fusions With and Without Recombinant Human Bone Morphogenetic Protein-2 in the US Medicare Population.

Authors:  Sue Lynn Myhre; Zorica Buser; Hans-Joerg Meisel; Darrel S Brodke; S Tim Yoon; Jeffrey C Wang; Jong-Beom Park; Jim A Youssef
Journal:  Global Spine J       Date:  2017-04-07

9.  Ectopic gas in the fibular graft after anterior cervical corpectomy and fusion.

Authors:  Satoshi Nozawa; Hiroki Kato; Masaya Kawaguchi; Asae Nozawa; Kazunari Yamada; Chizuo Iwai; Kazunari Fushimi; Kei Miyamoto; Hideo Hosoe; Katsuji Shimizu; Masayuki Matsuo; Haruhiko Akiyama
Journal:  BMC Musculoskelet Disord       Date:  2021-11-29       Impact factor: 2.362

10.  A comparison of contiguous two-level anterior cervical discectomy and fusion using a structural allograft versus a Polyetheretherketone (PEEK) cage: the results of a three-year follow-up.

Authors:  Ing How Moo; Carmen Jia Wen Kam; Maksim Wen Sheng Lai; William Yeo; Reuben Chee Cheong Soh
Journal:  BMC Musculoskelet Disord       Date:  2020-05-28       Impact factor: 2.362

  10 in total

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