Literature DB >> 16260144

Amino acid specificity in translation.

Taraka Dale1, Olke C Uhlenbeck.   

Abstract

Recent structural and biochemical experiments indicate that bacterial elongation factor Tu and the ribosomal A-site show specificity for both the amino acid and the tRNA portions of their aminoacyl-tRNA (aa-tRNA) substrates. These data are inconsistent with the traditional view that tRNAs are generic adaptors in translation. We hypothesize that each tRNA sequence has co-evolved with its cognate amino acid, such that all aa-tRNAs are translated uniformly.

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Year:  2005        PMID: 16260144     DOI: 10.1016/j.tibs.2005.10.006

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  41 in total

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2.  The codon specificity of eubacterial release factors is determined by the sequence and size of the recognition loop.

Authors:  David J Young; Christina D Edgar; Elizabeth S Poole; Warren P Tate
Journal:  RNA       Date:  2010-06-28       Impact factor: 4.942

Review 3.  Cellular mechanisms that control mistranslation.

Authors:  Noah M Reynolds; Beth A Lazazzera; Michael Ibba
Journal:  Nat Rev Microbiol       Date:  2010-12       Impact factor: 60.633

4.  Aminoacylation of tRNA 2'- or 3'-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases.

Authors:  Markus Englert; Sarath Moses; Michael Hohn; Jiqiang Ling; Patrick O'Donoghue; Dieter Söll
Journal:  FEBS Lett       Date:  2013-09-08       Impact factor: 4.124

5.  Emergence of the universal genetic code imprinted in an RNA record.

Authors:  Michael J Hohn; Hee-Sung Park; Patrick O'Donoghue; Michael Schnitzbauer; Dieter Söll
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-16       Impact factor: 11.205

Review 6.  Approaches for measuring the dynamics of RNA-protein interactions.

Authors:  Donny D Licatalosi; Xuan Ye; Eckhard Jankowsky
Journal:  Wiley Interdiscip Rev RNA       Date:  2019-08-20       Impact factor: 9.957

7.  Analysis of genomic tRNA sets from Bacteria, Archaea, and Eukarya points to anticodon-codon hydrogen bonds as a major determinant of tRNA compositional variations.

Authors:  Ilia Targanski; Vera Cherkasova
Journal:  RNA       Date:  2008-04-25       Impact factor: 4.942

8.  Anticodon recognition and discrimination by the alpha-helix cage domain of class I lysyl-tRNA synthetase.

Authors:  Jeffrey D Levengood; Hervé Roy; Ryuichiro Ishitani; Dieter Söll; Osamu Nureki; Michael Ibba
Journal:  Biochemistry       Date:  2007-08-31       Impact factor: 3.162

9.  Mechanisms of resistance to an amino acid antibiotic that targets translation.

Authors:  Sandro F Ataide; Sharnise N Wilson; Sandy Dang; Theresa E Rogers; Bappaditya Roy; Rajat Banerjee; Tina M Henkin; Michael Ibba
Journal:  ACS Chem Biol       Date:  2007-12-21       Impact factor: 5.100

10.  Electrostatics in the ribosomal tunnel modulate chain elongation rates.

Authors:  Jianli Lu; Carol Deutsch
Journal:  J Mol Biol       Date:  2008-09-16       Impact factor: 5.469

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