Literature DB >> 16257365

Overcoming challenges of using blood samples with gene expression microarrays to advance patient stratification in clinical trials.

Steve McPhail, Thomas J Goralski.   

Abstract

The advances in blood protocols enable improved identification of biomarkers based on RNA expression profiles and might assist us in realizing the promise of pharmacogenomics.

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Year:  2005        PMID： 16257365     DOI： 10.1016/S1359-6446(05)03644-5

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  3 in total

1.  Characterization of whole blood gene expression profiles as a sequel to globin mRNA reduction in patients with sickle cell disease.

Authors:  Nalini Raghavachari; Xiuli Xu; Peter J Munson; Mark T Gladwin
Journal:  PLoS One       Date:  2009-08-03       Impact factor: 3.240

2.  Deciphering normal blood gene expression variation--The NOWAC postgenome study.

Authors:  Vanessa Dumeaux; Karina S Olsen; Gregory Nuel; Ruth H Paulssen; Anne-Lise Børresen-Dale; Eiliv Lund
Journal:  PLoS Genet       Date:  2010-03-12       Impact factor: 5.917

3.  Identification of factors contributing to variability in a blood-based gene expression test.

Authors:  Michael R Elashoff; Rachel Nuttall; Philip Beineke; Michael H Doctolero; Mark Dickson; Andrea M Johnson; Susan E Daniels; Steven Rosenberg; James A Wingrove
Journal:  PLoS One       Date:  2012-07-03       Impact factor: 3.240
  3 in total

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