| Literature DB >> 16257206 |
Liming Shao1, Craig Abolin, Michael C Hewitt, Patrick Koch, Mark Varney.
Abstract
Tramadol is a centrally acting opioid analgesic structurally related to codeine and morphine. Analogs of tramadol with deuterium-for-hydrogen replacement at metabolically active sites were prepared and evaluated in vitro and in vivo.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16257206 DOI： 10.1016/j.bmcl.2005.10.024
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823