Literature DB >> 16254835

Two new antioxidant stilbene dimers, parthenostilbenins A and B from Parthenocissus tricuspidata.

Hyoung Ja Kim1, Muhammad Saleem, Seon Hee Seo, Changbae Jin, Yong Sup Lee.   

Abstract

The ethyl acetate fraction of an aqueous alcoholic extract from the stem of Parthenocissus tricuspidata yielded 11 known compounds (1-11) and two new stilbene dimers parthenostilbenins A (12) and B (13) upon purification either by preparative TLC or reversed phase HPLC. The structures of the new isolates were identified using a combination of FAB-MS and NMR. These compounds were assessed for antioxidant activities in three different bioassay systems. Among them, piceatannol showed the strongest inhibitory activity in these assay systems. Two new compounds, parthenostilbenins A (12) and B (13) inhibited lipid peroxidation (IC (50) = 20.35 +/- 1.22 and 18.68 +/- 0.51 microg/mL, respectively) in a rat liver homogenate.

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Year:  2005        PMID： 16254835     DOI： 10.1055/s-2005-871229

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


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