| Literature DB >> 16251321 |
William R Kirkpatrick1, Ana C Vallor, Robert K McAtee, Neil S Ryder, Annette W Fothergill, Michael G Rinaldi, Thomas F Patterson.
Abstract
Antagonistic effects of combination therapy using amphotericin B (AmB) with agents which block ergosterol synthesis are a concern. Terbinafine was evaluated with AmB to assess antagonism or synergy in a rabbit model of invasive aspergillosis. Terbinafine had relatively little activity but did not demonstrate antagonism against AmB in our model.Entities:
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Year: 2005 PMID: 16251321 PMCID: PMC1280177 DOI: 10.1128/AAC.49.11.4751-4753.2005
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191