Literature DB >> 16250900

The role of the ubiquitin-proteasome system in ER quality control.

Yihong Ye1.   

Abstract

Misfolded endoplasmic reticulum (ER) proteins are eliminated by the retrotranslocation pathway in eukaryotes, which is an important physiological adaptation to ER stress. This pathway can be hijacked by certain viruses to destroy folded cellular proteins, such as MHC class I heavy chain. Recent studies have highlighted the importance of the ubiquitin-proteasome system (UPS) in this process.

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Year:  2005        PMID: 16250900     DOI: 10.1042/EB0410099

Source DB:  PubMed          Journal:  Essays Biochem        ISSN: 0071-1365            Impact factor:   8.000


  13 in total

1.  Role of intramembrane charged residues in the quality control of unassembled T-cell receptor alpha-chains at the endoplasmic reticulum.

Authors:  Nia Soetandyo; Qiuyan Wang; Yihong Ye; Lianyun Li
Journal:  J Cell Sci       Date:  2010-04-01       Impact factor: 5.285

2.  Inhibition of p97-dependent protein degradation by Eeyarestatin I.

Authors:  Qiuyan Wang; Lianyun Li; Yihong Ye
Journal:  J Biol Chem       Date:  2008-01-16       Impact factor: 5.157

3.  Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.

Authors:  Wei Li; Daqi Tu; Lianyun Li; Thomas Wollert; Rodolfo Ghirlando; Axel T Brunger; Yihong Ye
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-17       Impact factor: 11.205

Review 4.  Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy.

Authors:  Yanfen Liu; Yihong Ye
Journal:  Cell Res       Date:  2011-05-03       Impact factor: 25.617

5.  Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin.

Authors:  Bo Gong; Li-Yun Zhang; Chi-Pui Pang; Dennis Shun-Chiu Lam; Gary Hin-Fai Yam
Journal:  Mol Vis       Date:  2009-12-19       Impact factor: 2.367

6.  Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy.

Authors:  Khaled Elmasry; Ahmed S Ibrahim; Heba Saleh; Nehal Elsherbiny; Sally Elshafey; Khaled A Hussein; Mohamed Al-Shabrawey
Journal:  Diabetologia       Date:  2018-02-21       Impact factor: 10.122

7.  The p97 ATPase dislocates MHC class I heavy chain in US2-expressing cells via a Ufd1-Npl4-independent mechanism.

Authors:  Nia Soetandyo; Yihong Ye
Journal:  J Biol Chem       Date:  2010-08-11       Impact factor: 5.157

8.  The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group.

Authors:  Qiuyan Wang; Bidhan A Shinkre; Jin-gu Lee; Marc A Weniger; Yanfen Liu; Weiping Chen; Adrian Wiestner; William C Trenkle; Yihong Ye
Journal:  PLoS One       Date:  2010-11-12       Impact factor: 3.240

9.  Dexamethasone-induced selenoprotein S degradation is required for adipogenesis.

Authors:  Choon Young Kim; Kee-Hong Kim
Journal:  J Lipid Res       Date:  2013-05-18       Impact factor: 5.922

10.  Imaging of radiation effects on cellular 26S proteasome function in situ.

Authors:  James M Brush; Kwanghee Kim; James W Sayre; William H McBride; Keisuke S Iwamoto
Journal:  Int J Radiat Biol       Date:  2009-06       Impact factor: 2.694

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