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Literature DB >> 16248085

Prosit, an online service to calculate pseudorotational parameters of nucleosides and nucleotides.

Guangyu Sun¹, Johannes H Voigt, Victor E Marquez, Marc C Nicklaus.

Abstract

The online service PROSIT (Pseudo-Rotational Online Service and Interactive Tool) is a free service available at http://cactus.nci.nci.gov/prosit/ that performs pseudorotational analysis of nucleosides(tides). PROSIT reads the 3D coordinates of nucleosides and returns the pseudorotational phase angle P, puckering amplitude vmax and other related information. As examples, the sugar conformations in a parallel-stranded guanine tetraplex and a four-way Holliday junction are presented here.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16248085 DOI： 10.1081/ncn-200059757

Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381

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Cited

4 in total

1. The conformationally constrained N-methanocarba-dT analogue adopts an unexpected C4'-exo sugar pucker in the structure of a DNA hairpin.

Authors: Pradeep S Pallan; Victor E Marquez; Martin Egli
Journal: Biochemistry Date: 2012-03-20 Impact factor: 3.162

Prosit, an online service to calculate pseudorotational parameters of nucleosides and nucleotides.

1. The conformationally constrained N-methanocarba-dT analogue adopts an unexpected C4'-exo sugar pucker in the structure of a DNA hairpin.

2. Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach.

3. Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase.

Review 4. The structural diversity of artificial genetic polymers.