Literature DB >> 16248078

A novel amino-on CPG-support for the synthesis of 3'-aminoalkylated oligonucleotides.

Michael Leuck1, Rubina Glare, Nicole Zien, Matthias Paul, Andreas Wolter.   

Abstract

The synthesis of a novel amino-ON CPG support and its application in the synthesis of 3'-aminoalkylated oligonucleotides is reported. The release of oligonucleotides with free 3'-amino groups is accomplished by treatment with concentrated ammonia for 2 h at 55 degrees C.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16248078     DOI: 10.1081/ncn-200059388

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  1 in total

1.  Chemically defined polyethylene glycol siRNA conjugates with enhanced gene silencing effect.

Authors:  Zuzana Gaziova; Volker Baumann; Anna-Maria Winkler; Johannes Winkler
Journal:  Bioorg Med Chem       Date:  2014-02-20       Impact factor: 3.641

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.