Literature DB >> 1624563

Detection of borreliacidal antibodies in hamsters by using flow cytometry.

K F Sachsenmeier1, K Schell, L W Morrissey, D R Pennell, R M West, S M Callister, R F Schell.   

Abstract

Flow cytometry can be used to detect antibody that kills Borrelia burgdorferi. Borreliacidal activity was detected within 3 h of incubating B. burgdorferi with immune serum and complement. Right-angle light scatter and propidium iodide fluorescence were the cytometric parameters which correlated best with in vitro killing of B. burgdorferi. Flow cytometry is a rapid method for determining the presence of borreliacidal activity and may lead to a better serodiagnostic test for the detection of Lyme disease.

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Year:  1992        PMID： 1624563      PMCID： PMC265310          DOI： 10.1128/jcm.30.6.1457-1461.1992

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  22 in total

1.  Characterization of the protective antibody response to Borrelia burgdorferi in experimentally infected LSH hamsters.

Authors:  J L Schmitz; R F Schell; S D Lovrich; S M Callister; J E Coe
Journal:  Infect Immun       Date:  1991-06       Impact factor: 3.441

2.  Serodiagnosis of early Lyme disease: analysis of IgM and IgG antibody responses by using an antibody-capture enzyme immunoassay.

Authors:  V P Berardi; K E Weeks; A C Steere
Journal:  J Infect Dis       Date:  1988-10       Impact factor: 5.226

3.  Antigenic variability of Borrelia burgdorferi.

Authors:  B Wilske; V Preac-Mursic; G Schierz; R Kühbeck; A G Barbour; M Kramer
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

4.  Fluoroimmunoassay studies with solubilized antigens from Borrelia burgdorferi.

Authors:  K E Hechemy; H L Harris; J A Wethers; R W Stevens; B R Stock; A A Reilly; J L Benach
Journal:  J Clin Microbiol       Date:  1989-08       Impact factor: 5.948

5.  Serology of Lyme disease.

Authors:  M F Muhlemann; D J Wright; C Black
Journal:  Lancet       Date:  1986-03-08       Impact factor: 79.321

6.  Measurement of antibodies to the Borrelia burgdorferi flagellum improves serodiagnosis in Lyme disease.

Authors:  K Hansen; P Hindersson; N S Pedersen
Journal:  J Clin Microbiol       Date:  1988-02       Impact factor: 5.948

7.  The spirochetal etiology of Lyme disease.

Authors:  A C Steere; R L Grodzicki; A N Kornblatt; J E Craft; A G Barbour; W Burgdorfer; G P Schmid; E Johnson; S E Malawista
Journal:  N Engl J Med       Date:  1983-03-31       Impact factor: 91.245

Review 8.  Lyme disease.

Authors:  A C Steere
Journal:  N Engl J Med       Date:  1989-08-31       Impact factor: 91.245

9.  Comparison of immunoblotting and indirect enzyme-linked immunosorbent assay using different antigen preparations for diagnosing early Lyme disease.

Authors:  R L Grodzicki; A C Steere
Journal:  J Infect Dis       Date:  1988-04       Impact factor: 5.226

10.  Lyme disease assay which detects killed Borrelia burgdorferi.

Authors:  S M Callister; R F Schell; S D Lovrich
Journal:  J Clin Microbiol       Date:  1991-09       Impact factor: 5.948
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  3 in total

Review 1.  Uses of flow cytometry in virology.

Authors:  J J McSharry
Journal:  Clin Microbiol Rev       Date:  1994-10       Impact factor: 26.132

2.  Differentiation of borreliacidal activity caused by immune serum or antimicrobial agents by flow cytometry.

Authors:  Y F Liu; L C Lim; K Schell; S D Lovrich; S M Callister; R F Schell
Journal:  Clin Diagn Lab Immunol       Date:  1994-03

3.  Detection of borreliacidal antibody by using acridine orange and flow cytometry.

Authors:  L C Lim; Y F Liu; K Schell; S D Lovrich; S M Callister; R F Schell
Journal:  Clin Diagn Lab Immunol       Date:  1994-01
  3 in total

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