Literature DB >> 16243237

Nasal airflow and olfactory function after the repair of cleft palate (with and without cleft lip).

Noam Grossmann1, Ilana Brin, Dror Aizenbud, Jean-Yves Sichel, Ruth Gross-Isseroff, Jacob Steiner.   

Abstract

OBJECTIVE: The objective of this study was to examine nasal airflow and olfactory functions in patients with repaired cleft palate compared with matching normal controls. STUDY
DESIGN: The all-cleft group consisted of 25 patients with hard palate cleft comprising 15 patients with unilateral cleft palate and lip (UCLP); 2 with CP but no cleft lip (UCLP subgroup) and 8 patients with bilateral cleft lip and palate (BCLP subgroup). All had had surgical correction of the palate in infancy. The control group consisted of 20 nonaffected orthodontic patients. The median age of both groups was 14 years. The tests included the following: (1) nasal airflow measured by anterior rhinomanometry, (2) smell threshold for isoamyl-acetate determined using a 3-way forced choice method, (3) a self-administered questionnaire regarding the subjective perception of smell sense function, and (4) orthonasal and retronasal smell identification (correct/incorrect) and hedonics using visual analog scale (VAS).
RESULTS: The respective test results follow. (1) When compared with the control group, the total airflow in the UCLP subgroup was significantly lower especially on the affected side; while in the BCLP subgroup it was lower than in the control group bilaterally. No significant difference was found between the cleft side of UCLP and BCLP subgroups. (2) The smell threshold of the UCLP subgroup was significantly higher than that of the control group and BCLP subgroup. No significant differences were found between right and left nostrils within the BCLP patients and between them and the control group. (3) No difference was found between the groups regarding the subjective perception of smell. (4) No significant differences were found between the UCLP and BCLP subgroups and between the all-cleft group and the control group, except for one item, regarding orthonasal and retronasal smell identification and hedonics.
CONCLUSION: Although nasal airflow is significantly lower and the smell threshold higher on the cleft side, the day-to-day function of the sense of smell of cleft patients is similar to that of normal controls.

Entities:  

Mesh:

Year:  2005        PMID: 16243237     DOI: 10.1016/j.tripleo.2005.02.074

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


  6 in total

1.  Evidence of olfactory deficits as part of the phenotypic spectrum of nonsyndromic orofacial clefting.

Authors:  Maureen A May; Carla A Sanchez; Frederic W B Deleyiannis; Mary L Marazita; Seth M Weinberg
Journal:  J Craniofac Surg       Date:  2015-01       Impact factor: 1.046

2.  Facial Characteristics and Olfactory Dysfunction: Two Endophenotypes Related to Nonsyndromic Cleft Lip and/or Palate.

Authors:  J Roosenboom; I Saey; H Peeters; K Devriendt; P Claes; G Hens
Journal:  Biomed Res Int       Date:  2015-05-06       Impact factor: 3.411

3.  Disentangling interoception: insights from focal strokes affecting the perception of external and internal milieus.

Authors:  Blas Couto; Federico Adolfi; Lucas Sedeño; Alejo Salles; Andrés Canales-Johnson; Pablo Alvarez-Abut; Indira Garcia-Cordero; Marcos Pietto; Tristan Bekinschtein; Mariano Sigman; Facundo Manes; Agustin Ibanez
Journal:  Front Psychol       Date:  2015-05-01

4.  Computational Analysis of the Mature Unilateral Cleft Lip Nasal Deformity on Nasal Patency.

Authors:  Dennis O Frank-Ito; David J Carpenter; Tracy Cheng; Yash J Avashia; David A Brown; Adam Glener; Alexander Allori; Jeffrey R Marcus
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-05-16

5.  Evaluation of Oral Health-related Quality of Life for Adult Individuals with Cleft Lip and/or Palate Using OHIP-49 and Compared with a Control Group: A Cross-Sectional Study.

Authors:  Marwan Aljohani; Falah Alshammari; Hamdan Alamri; Abdullah Bin Rahmah; Martin Ashley; Julian Yates
Journal:  J Int Soc Prev Community Dent       Date:  2021-06-26

Review 6.  Olfactory perception in children.

Authors:  E Leslie Cameron
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2018-03-21
  6 in total

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