| Literature DB >> 16241902 |
A D'Yachkov1, Frank Hwang, Antony Macula, Pavel Vilenkin, Chih-Wen Weng.
Abstract
The screening of data sets for "positive data objects" is essential to modern technology. A (group) test that indicates whether a positive data object is in a specific subset or pool of the dataset can greatly facilitate the identification of all the positive data objects. A collection of tested pools is called a pooling design. Pooling designs are standard experimental tools in many biotechnical applications. In this paper, we use the (linear) subspace relation coupled with the general concept of a "containment matrix" to construct pooling designs with surprisingly high degrees of error correction (detection.) Error-correcting pooling designs are important to biotechnical applications where error rates often are as high as 15%. What is also surprising is that the rank of the pooling design containment matrix is independent of the number of positive data objects in the dataset.Mesh:
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Year: 2005 PMID: 16241902 DOI: 10.1089/cmb.2005.12.1129
Source DB: PubMed Journal: J Comput Biol ISSN: 1066-5277 Impact factor: 1.479