OBJECTIVES: Rhino-orbito-cerebral mucormycosis (ROCM) is an uncommon, potentially lethal infection that occurs mostly in immunocompromised hosts. The seasonal occurrence of ROCM was studied in two of Israel's largest medical centers. METHODS: A total of 36 patients were seen during a 25-year period in this retrospective bi-institutional cohort study. Meteorologic data were obtained and analyzed for a possible linkage of infection with precipitation and temperature. RESULTS: Twenty-one of the 36 patients (58%) presented between the months of August and October, and 27 patients (75%) presented between the months of August and December. A peak incidence of ROCM was noted in the month of September (13/36 patients; 36%). No association was noted between meteorologic conditions and the incidence of ROCM infection. CONCLUSIONS: A consistent seasonal peak was observed in ROCM. Heightened awareness is important for early recognition and treatment of this disease.
OBJECTIVES:Rhino-orbito-cerebral mucormycosis (ROCM) is an uncommon, potentially lethal infection that occurs mostly in immunocompromised hosts. The seasonal occurrence of ROCM was studied in two of Israel's largest medical centers. METHODS: A total of 36 patients were seen during a 25-year period in this retrospective bi-institutional cohort study. Meteorologic data were obtained and analyzed for a possible linkage of infection with precipitation and temperature. RESULTS: Twenty-one of the 36 patients (58%) presented between the months of August and October, and 27 patients (75%) presented between the months of August and December. A peak incidence of ROCM was noted in the month of September (13/36 patients; 36%). No association was noted between meteorologic conditions and the incidence of ROCM infection. CONCLUSIONS: A consistent seasonal peak was observed in ROCM. Heightened awareness is important for early recognition and treatment of this disease.
Authors: Shobini Sivagnanam; Dhruba J Sengupta; Daniel Hoogestraat; Rupali Jain; Zach Stednick; David N Fredricks; Paul Hendrie; Estella Whimbey; Sara T Podczervinski; Elizabeth M Krantz; Jeffrey S Duchin; Steven A Pergam Journal: Antimicrob Resist Infect Control Date: 2017-12-06 Impact factor: 4.887
Authors: Kathleen P Hartnett; Brendan R Jackson; Kiran M Perkins; Janet Glowicz; Janna L Kerins; Stephanie R Black; Shawn R Lockhart; Bryan E Christensen; Karlyn D Beer Journal: J Fungi (Basel) Date: 2019-07-24