Literature DB >> 16240301

Scaffolds for microtubule inhibition through extensive modification of the epothilone template.

Frédéric Cachoux1, Thomas Isarno, Markus Wartmann, Karl-Heinz Altmann.   

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Year:  2005        PMID: 16240301     DOI: 10.1002/anie.200501760

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  2 in total

Review 1.  Conformation-activity relationships of polyketide natural products.

Authors:  Erik M Larsen; Matthew R Wilson; Richard E Taylor
Journal:  Nat Prod Rep       Date:  2015-08       Impact factor: 13.423

2.  Characterizing the Epothilone Binding Site on β-Tubulin by Photoaffinity Labeling: Identification of β-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin.

Authors:  Adwait R Ranade; LeeAnn Higgins; Todd W Markowski; Nicole Glaser; Dmitry Kashin; Ruoli Bai; Kwon Ho Hong; Ernest Hamel; Gerhard Höfle; Gunda I Georg
Journal:  J Med Chem       Date:  2016-03-17       Impact factor: 7.446

  2 in total

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