Literature DB >> 16239901

Immunization without needles.

Samir Mitragotri1.   

Abstract

Most current immunization procedures make use of needles and syringes for vaccine administration. With the increase in the number of immunizations that children around the world routinely receive, health organizations are beginning to look for safer alternatives that reduce the risk of cross-contamination that arises from needle reuse. This article focuses on contemporary developments in needle-free methods of immunization, such as liquid-jet injectors, topical application to the skin, oral pills and nasal sprays.

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Year:  2005        PMID: 16239901     DOI: 10.1038/nri1728

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN: 1474-1733            Impact factor:   53.106


  98 in total

1.  Bacillus Calmette-Guérin vaccination using a microneedle patch.

Authors:  Yasuhiro Hiraishi; Subhadra Nandakumar; Seong-O Choi; Jeong Woo Lee; Yeu-Chun Kim; James E Posey; Suraj B Sable; Mark R Prausnitz
Journal:  Vaccine       Date:  2011-01-28       Impact factor: 3.641

Review 2.  Recombinant IgA production for mucosal passive immunization, advancing beyond the hurdles.

Authors:  Vikram Virdi; Paloma Juarez; Veronique Boudolf; Ann Depicker
Journal:  Cell Mol Life Sci       Date:  2015-10-28       Impact factor: 9.261

3.  Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets.

Authors:  Anubhav Arora; Itzhak Hakim; Joy Baxter; Ruben Rathnasingham; Ravi Srinivasan; Daniel A Fletcher; Samir Mitragotri
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-06       Impact factor: 11.205

Review 4.  Nucleic acid delivery into skin for the treatment of skin disease: Proofs-of-concept, potential impact, and remaining challenges.

Authors:  Michael Zakrewsky; Sunny Kumar; Samir Mitragotri
Journal:  J Control Release       Date:  2015-09-15       Impact factor: 9.776

Review 5.  New routes for allergen immunotherapy.

Authors:  Pål Johansen; Seraina von Moos; Deepa Mohanan; Thomas M Kündig; Gabriela Senti
Journal:  Hum Vaccin Immunother       Date:  2012-10-01       Impact factor: 3.452

6.  An electrically active microneedle array for electroporation.

Authors:  Seong-O Choi; Yeu Chun Kim; Jung-Hwan Park; Joshua Hutcheson; Harvinder S Gill; Yong-Kyu Yoon; Mark R Prausnitz; Mark G Allen
Journal:  Biomed Microdevices       Date:  2010-04       Impact factor: 2.838

7.  Enhanced memory responses to seasonal H1N1 influenza vaccination of the skin with the use of vaccine-coated microneedles.

Authors:  Yeu-Chun Kim; Fu-Shi Quan; Dae-Goon Yoo; Richard W Compans; Sang-Moo Kang; Mark R Prausnitz
Journal:  J Infect Dis       Date:  2010-01-15       Impact factor: 5.226

8.  Characterization of stability and nasal delivery systems for immunization with nanoemulsion-based vaccines.

Authors:  Paul E Makidon; Shraddha S Nigavekar; Anna U Bielinska; Nicholas Mank; Abhishek M Shetty; Julie Suman; Jessica Knowlton; Andrzej Myc; Trent Rook; James R Baker
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2010-04       Impact factor: 2.849

9.  Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection.

Authors:  Karina A Pasquevich; Silvia M Estein; Clara García Samartino; Clara García Samartino; Astrid Zwerdling; Lorena M Coria; Paula Barrionuevo; Carlos A Fossati; Guillermo H Giambartolomei; Juliana Cassataro
Journal:  Infect Immun       Date:  2008-11-03       Impact factor: 3.441

10.  Dose-dependent protection against or exacerbation of disease by a polylactide glycolide microparticle-adsorbed, alphavirus-based measles virus DNA vaccine in rhesus macaques.

Authors:  Chien-Hsiung Pan; Nitya Nair; Robert J Adams; M Christine Zink; Eun-Young Lee; Fernando P Polack; Manmohan Singh; Derek T O'Hagan; Diane E Griffin
Journal:  Clin Vaccine Immunol       Date:  2008-02-20
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