Literature DB >> 16239584

Immunization with recombinant Streptococcus pneumoniae neuraminidase NanA protects chinchillas against nasopharyngeal colonization.

H H Tong1, D Li, S Chen, J P Long, T F DeMaria.   

Abstract

Immunization with recombinant S. pneumoniae neuraminidase NanA (rNanA) resulted in a significant reduction in pneumococcal colonization in the chinchilla model. The bacteria were eliminated from the nasopharynx 1 week earlier than that from the control cohort. Our data suggest that rNanA affords protection against pneumococcal nasopharyngeal colonization.

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Year:  2005        PMID： 16239584      PMCID： PMC1273864          DOI： 10.1128/IAI.73.11.7775-7778.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  32 in total

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  17 in total

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10.  Characterization of Pneumococcal Genes Involved in Bloodstream Invasion in a Mouse Model.

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