| Literature DB >> 16239580 |
Andre Kipnis1, Scott Irwin, Angelo A Izzo, Randall J Basaraba, Ian M Orme.
Abstract
In the lungs of mice vaccinated with Mycobacterium bovis BCG, there was an accumulation of CD4 cells expressing the activated effector phenotype CD44hi CD62 ligandlo) (CD62Llo) which were capable of secreting gamma interferon. Upon cell transfer, however, cells expressing a resting/naïve phenotype (CD44lo CD62Lhi) were capable of protecting the recipients from a virulent challenge infection, suggesting the emergence of T-cell memory from within this subset.Entities:
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Year: 2005 PMID: 16239580 PMCID: PMC1273888 DOI: 10.1128/IAI.73.11.7759-7764.2005
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441