Literature DB >> 16239501

Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway.

Thomas W Spahn1, Hans-Pietro Eugster, Adriano Fontana, Wolfram Domschke, Torsten Kucharzik.   

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Year:  2005        PMID： 16239501      PMCID： PMC1273913          DOI： 10.1128/IAI.73.11.7077-7088.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


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  72 in total

1.  B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion.

Authors:  Ping Yu; Yang Wang; Robert K Chin; Luisa Martinez-Pomares; Siamon Gordon; Marie H Kosco-Vibois; Jason Cyster; Yang-Xin Fu
Journal:  J Immunol       Date:  2002-05-15       Impact factor: 5.422

2.  Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice.

Authors:  M B Alimzhanov; D V Kuprash; M H Kosco-Vilbois; A Luz; R L Turetskaya; A Tarakhovsky; K Rajewsky; S A Nedospasov; K Pfeffer
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-19       Impact factor: 11.205

3.  Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor.

Authors:  M Pasparakis; L Alexopoulou; M Grell; K Pfizenmaier; H Bluethmann; G Kollias
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

Review 4.  Network communications: lymphotoxins, LIGHT, and TNF.

Authors:  Carl F Ware
Journal:  Annu Rev Immunol       Date:  2005       Impact factor: 28.527

5.  The lymphotoxin-beta receptor is critical for control of murine Citrobacter rodentium-induced colitis.

Authors:  Thomas W Spahn; Christian Maaser; Lars Eckmann; Jan Heidemann; Andreas Lügering; Rodney Newberry; Wolfram Domschke; Hermann Herbst; Torsten Kucharzik
Journal:  Gastroenterology       Date:  2004-11       Impact factor: 22.682

6.  Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection.

Authors:  Christian R Engwerda; Manabu Ato; Simona Stäger; Clare E Alexander; Amanda C Stanley; Paul M Kaye
Journal:  Am J Pathol       Date:  2004-12       Impact factor: 4.307

7.  The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function.

Authors:  Jing Wang; Amy Foster; Robert Chin; Ping Yu; Yonglian Sun; Yang Wang; Klaus Pfeffer; Yang-Xin Fu
Journal:  Eur J Immunol       Date:  2002-07       Impact factor: 5.532

8.  Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria.

Authors:  Christian R Engwerda; Tracey L Mynott; Sanjeet Sawhney; J Brian De Souza; Quentin D Bickle; Paul M Kaye
Journal:  J Exp Med       Date:  2002-05-20       Impact factor: 14.307

9.  Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen.

Authors:  V N Ngo; H Korner; M D Gunn; K N Schmidt; D S Riminton; M D Cooper; J L Browning; J D Sedgwick; J G Cyster
Journal:  J Exp Med       Date:  1999-01-18       Impact factor: 14.307

10.  Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis.

Authors:  Stefanie Scheu; Judith Alferink; Tobias Pötzel; Winfried Barchet; Ulrich Kalinke; Klaus Pfeffer
Journal:  J Exp Med       Date:  2002-06-17       Impact factor: 14.307
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  16 in total

1.  Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.

Authors:  Yanhui Xu; Andrew S Flies; Dallas B Flies; Gefeng Zhu; Sudarshan Anand; Sarah J Flies; Haiying Xu; Robert A Anders; Wayne W Hancock; Lieping Chen; Koji Tamada
Journal:  Blood       Date:  2006-12-19       Impact factor: 22.113

Review 2.  Restoring immune defenses via lymphotoxin signaling: lessons from cytomegalovirus.

Authors:  Theresa A Banks; Sandra Rickert; Carl F Ware
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

3.  B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity.

Authors:  E Ashley Moseman; Matteo Iannacone; Lidia Bosurgi; Elena Tonti; Nicolas Chevrier; Alexei Tumanov; Yang-Xin Fu; Nir Hacohen; Ulrich H von Andrian
Journal:  Immunity       Date:  2012-03-01       Impact factor: 31.745

Review 4.  Lymphotoxin in physiology of lymphoid tissues - Implication for antiviral defense.

Authors:  Ekaterina P Koroleva; Yang-Xin Fu; Alexei V Tumanov
Journal:  Cytokine       Date:  2016-09-09       Impact factor: 3.861

5.  The absence of cutaneous lymph nodes results in a Th2 response and increased susceptibility to Leishmania major infection in mice.

Authors:  Jan M Ehrchen; Johannes Roth; Kirsten Roebrock; Georg Varga; Wolfram Domschke; Rodney Newberry; Clemens Sorg; Carsten Müller-Tidow; Cord Sunderkötter; Torsten Kucharzik; Thomas W Spahn
Journal:  Infect Immun       Date:  2008-07-14       Impact factor: 3.441

6.  Association of LT-alpha Ala252Gly gene polymorphism and the genetic predisposition of coronary heart disease in Chinese.

Authors:  Hanxiang Gao; Zheng Zhang; Jin Zhang; Nan Zhao; Qiang Li; Ming Bai
Journal:  Mol Biol Rep       Date:  2009-04-14       Impact factor: 2.316

Review 7.  Ectopic lymphoid tissues and local immunity.

Authors:  Damian M Carragher; Javier Rangel-Moreno; Troy D Randall
Journal:  Semin Immunol       Date:  2008-02-19       Impact factor: 11.130

8.  Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity.

Authors:  Emma T Cadman; Asmahan Y Abdallah; Cécile Voisine; Anne-Marit Sponaas; Patrick Corran; Tracey Lamb; Douglas Brown; Francis Ndungu; Jean Langhorne
Journal:  Infect Immun       Date:  2008-06-16       Impact factor: 3.441

9.  Resistance of chemokine receptor 6-deficient mice to Yersinia enterocolitica infection: evidence of defective M-cell formation in vivo.

Authors:  Sabine Westphal; Andreas Lügering; Julia von Wedel; Christof von Eiff; Christian Maaser; Thomas Spahn; Gerhard Heusipp; M Alexander Schmidt; Hermann Herbst; Ifor R Williams; Wolfram Domschke; Torsten Kucharzik
Journal:  Am J Pathol       Date:  2008-02-07       Impact factor: 4.307

10.  The association of lymphotoxin-beta receptor with the subsequent diagnosis of incident gastrointestinal cancer: results from the Dallas Heart Study.

Authors:  Colin P Bergstrom; Muhammad S Beg; Colby Ayers; Arjun Gupta; Ian J Neeland
Journal:  J Gastrointest Oncol       Date:  2020-02
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