| Literature DB >> 1623916 |
F Kamali1, L Adriaens, M L Huang, R Woestenborghs, M Emanuel, M D Rawlins.
Abstract
The pharmacokinetics of loperamide, after oral administration of increasing doses (1 to 16 mg) of loperamide oxide, has been investigated in 10 healthy male volunteers, using a randomised cross-over design. Comparison of the maximum plasma loperamide concentration and AUC demonstrated that the bioavailability of loperamide was proportional to the dose of loperamide oxide administered.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1623916 DOI： 10.1007/bf00265940
Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953