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Literature DB >> 16238304

A model study toward the total synthesis of N-deacetyllappaconitine.

Douglass F Taber¹, Jiang-Lin Liang, Bei Chen, Lisi Cai.

Abstract

[reaction: see text] A model study leading to the preparation of the AEF rings of N-deacetyllappaconitine is described. The conjugate addition to the alpha-alkyl cyclohexenone 10 proceeded with high diastereocontrol. The Mannich cyclization of 16 to 4 was accomplished by heating with Rexyn-300 and Na(2)SO(4).

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16238304 PMCID： PMC3248817 DOI： 10.1021/jo051155y

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

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