Literature DB >> 16237854

All silent on the transcription front.

Nicole Rusk.   

Abstract

Peptide nucleic acid (PNA) or RNA directed against the genomic DNA sequence around the transcription start site effectively knock down the expression of the targeted gene and make for an effective addition to the arsenal of gene silencing methods.

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Year:  2005        PMID: 16237854     DOI: 10.1038/nmeth1005-726b

Source DB:  PubMed          Journal:  Nat Methods        ISSN: 1548-7091            Impact factor:   28.547


  1 in total

1.  (α,α-dimethyl)glycyl (dmg) PNAs: achiral PNA analogs that form stronger hybrids with cDNA relative to isosequential RNA.

Authors:  Aland Gourishankar; Krishna N Ganesh
Journal:  Artif DNA PNA XNA       Date:  2012 Jan-Mar
  1 in total

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