Literature DB >> 16236509

N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase.

Sabine Gavalda1, Rémi Braga, Chantal Dax, Alain Vigroux, Casimir Blonski.   

Abstract

Dihydroxyacetone-phosphate and phosphonate derivatives were synthesized bearing a N-sulfonyl hydroxamate moiety. The phosphate derivatives represent competitive inhibitors for the class II-FBP aldolase catalyzed reaction, while the phosphonate isosteres are comparatively weaker inhibitors.

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Year:  2005        PMID： 16236509     DOI： 10.1016/j.bmcl.2005.09.006

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  A metabolic operon in extraintestinal pathogenic Escherichia coli promotes fitness under stressful conditions and invasion of eukaryotic cells.

Authors:  Géraldine Rouquet; Gaëlle Porcheron; Claire Barra; Maryline Répérant; Nathalie K Chanteloup; Catherine Schouler; Philippe Gilot
Journal:  J Bacteriol       Date:  2009-04-17       Impact factor: 3.490

Review 2.  Targeting Metalloenzymes for Therapeutic Intervention.

Authors:  Allie Y Chen; Rebecca N Adamek; Benjamin L Dick; Cy V Credille; Christine N Morrison; Seth M Cohen
Journal:  Chem Rev       Date:  2018-09-07       Impact factor: 60.622

3.  A noncompetitive inhibitor for Mycobacterium tuberculosis's class IIa fructose 1,6-bisphosphate aldolase.

Authors:  Glenn C Capodagli; Wafik G Sedhom; Mary Jackson; Kateri A Ahrendt; Scott D Pegan
Journal:  Biochemistry       Date:  2013-12-24       Impact factor: 3.162

4.  Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.

Authors:  Scott D Pegan; Kamolchanok Rukseree; Scott G Franzblau; Andrew D Mesecar
Journal:  J Mol Biol       Date:  2009-01-10       Impact factor: 5.469

5.  Structural and functional characterization of methicillin-resistant Staphylococcus aureus's class IIb fructose 1,6-bisphosphate aldolase.

Authors:  Glenn C Capodagli; Stephen A Lee; Kyle J Boehm; Kristin M Brady; Scott D Pegan
Journal:  Biochemistry       Date:  2014-11-21       Impact factor: 3.162

6.  The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues.

Authors:  Federica Pisaneschi; Yu-Hsi Lin; Paul G Leonard; Nikunj Satani; Victoria C Yan; Naima Hammoudi; Sudhir Raghavan; Todd M Link; Dimitra K Georgiou; Barbara Czako; Florian L Muller
Journal:  Molecules       Date:  2019-07-09       Impact factor: 4.411
  6 in total

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