Literature DB >> 16236376

Pentoxifylline and vitamin E combination for superficial radiation-induced fibrosis: a phase II clinical trial.

Peiman Haddad1, Bita Kalaghchi, Farnaz Amouzegar-Hashemi.   

Abstract

We treated 34 radiation-induced superficial fibrotic lesions with pentoxifylline and vitamin E for 3 months. Mean surface area of the lesions decreased from 112 to 65 cm(2) after treatment (P<0.001). A subgroup of 21 fibrotic lesions received the medications for 6 months, in which surface area decreased from 80 to 27 cm(2) (P<0.001). Pentoxifylline-vitamin E combination improved radiation-induced fibrosis.

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Year:  2005        PMID： 16236376     DOI： 10.1016/j.radonc.2005.09.014

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN： 0167-8140            Impact factor:   6.280


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