Literature DB >> 16235891

Synthesis of biologically active amines via rhodium-bisphosphite-catalyzed hydroaminomethylation.

John R Briggs1, Jerzy Klosin, Gregory T Whiteker.   

Abstract

[reaction: see text] We report the use of a highly regioselective rhodium-bisphosphite catalyst for olefin hydroaminomethylation. This catalyst system was successfully applied in the synthesis of two biologically active tertiary amines, ibutilide and aripiprazole.

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Year:  2005        PMID: 16235891     DOI: 10.1021/ol050848y

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  A Multicatalytic Approach to the Hydroaminomethylation of α-Olefins.

Authors:  Steven Hanna; Jeffrey C Holder; John F Hartwig
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-15       Impact factor: 15.336

2.  Dithienopyrrole Derivatives with Nitronyl Nitroxide Radicals and Their Oxidation to Cationic High-Spin Molecules.

Authors:  Kubandiran Kolanji; Martin Baumgarten
Journal:  Chemistry       Date:  2020-02-28       Impact factor: 5.236

3.  Diene hydroaminomethylation via ruthenium-catalyzed C-C bond forming transfer hydrogenation: beyond carbonylation.

Authors:  Susumu Oda; Jana Franke; Michael J Krische
Journal:  Chem Sci       Date:  2015-11-17       Impact factor: 9.825

  3 in total

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