Literature DB >> 16235839

[Long-term prognosis after surgery for pathological stage III lung cancer].

K Togashi1, M Saito, H Shinohara, T Wakabayashi, F Asami.   

Abstract

OBJECTIVE: We studied for the purpose of revealing the long-term prognosis of the surgical treatment for pathological stage III lung cancer.
METHOD: Two hundred fifty-four patients with pathological stage III disease who underwent surgical procedures in our hospital from 1981 to 2000 were investigated retrospectively.
RESULTS: The 5- and 10-year survival rates of 144 patients with stage IIIA disease were 35 and 25%, while those of 110 patients with IIIB disease were 30 and 16%. The 5- and 10-year survival rates were 40 and 27% for 52 patients with T1N2 disease, 33 and 23% for 70 patients with T2N2 disease, 34 and 0% for 9 patients with T3N1 disease, and 33 and 26% for 13 patients with T3N2 disease, respectively. In the patients with IIIB disease, the 5- and 10-year survival rates of 56 patients only with pml were 47 and 26%, those of the other patients were 9 and 0%. There is significant difference among them (p < 0.0001). In 54 patients with IIIB disease in addition to pm1, the 5-year survival rates of 19 patients with exploration only and the other patients were 7 and 14%, respectively. There were no 10-year survivors in both groups.
CONCLUSION: The long-term prognosis of pathological stage III disease was still not satisfactory. Therefore, we should make efforts to get a sufficient informed-consent before the surgery for the patients with stage III disease.

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Year:  2005        PMID: 16235839

Source DB:  PubMed          Journal:  Kyobu Geka        ISSN: 0021-5252


  1 in total

1.  Combining antiangiogenic therapy with neoadjuvant chemotherapy increases treatment efficacy in stage IIIA (N2) non-small cell lung cancer without increasing adverse effects.

Authors:  Xiaoliang Zhao; Yanjun Su; Jian You; Liqun Gong; Zhenfa Zhang; Meng Wang; Zhenqing Zhao; Zhen Zhang; Xiaolin Li; Changli Wang
Journal:  Oncotarget       Date:  2016-09-20
  1 in total

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