Literature DB >> 16235573

BeadArray-based solutions for enabling the promise of pharmacogenomics.

Jian-Bing Fan1, Sean X Hu, William C Craumer, David L Barker.   

Abstract

A "one-size-fits-all" approach continues to characterize today's healthcare paradigm. But emergent rules, information, genomics tools, and economics are driving a fundamental and inevitable shift to a more personalized world of medicine. In this new world, the interests of insurers, regulators, suppliers, healthcare providers, and most important, patients, will have converged. The new goal will be the right treatment for the right individual at the right time. In this world, personalized medicine, through pharmacogenomics (PGx), will be the new healthcare paradigm. We will briefly examine healthcare trends and current opportunities for PGx development. We will then demonstrate how microarray technologies-among them bead-based approaches-have emerged as a key enabler for bringing home the promise of PGx.

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Year:  2005        PMID: 16235573

Source DB:  PubMed          Journal:  Biotechniques        ISSN: 0736-6205            Impact factor:   1.993


  7 in total

Review 1.  DNA microarray-based gene expression profiling of estrogenic chemicals.

Authors:  Ryoiti Kiyama; Yun Zhu
Journal:  Cell Mol Life Sci       Date:  2014-01-08       Impact factor: 9.261

Review 2.  Basic concepts of microarrays and potential applications in clinical microbiology.

Authors:  Melissa B Miller; Yi-Wei Tang
Journal:  Clin Microbiol Rev       Date:  2009-10       Impact factor: 26.132

3.  No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density.

Authors:  Celine M Vachon; Jingmei Li; Christopher G Scott; Per Hall; Kamila Czene; Xianshu Wang; Jianjun Liu; Zachary S Fredericksen; David N Rider; Fang-Fang Wu; Janet E Olson; Julie M Cunningham; Kristen N Stevens; Thomas A Sellers; Shane V Pankratz; Fergus J Couch
Journal:  Breast Cancer Res       Date:  2012-01-07       Impact factor: 6.466

4.  Regular Multivitamin Supplement Use, Single Nucleotide Polymorphisms in ATIC, SHMT2, and SLC46A1, and Risk of Ovarian Carcinoma.

Authors:  Linda E Kelemen; Qinggang Wang; Irina Dinu; Robert A Vierkant; Ya-Yu Tsai; Julie M Cunningham; Catherine M Phelan; Brooke L Fridley; Ernest K Amankwah; Edwin S Iversen; Andrew Berchuck; Joellen M Schildkraut; Ellen L Goode; Thomas A Sellers
Journal:  Front Genet       Date:  2012-03-19       Impact factor: 4.599

5.  Microarray in parasitic infections.

Authors:  Rakesh Sehgal; Shubham Misra; Namrata Anand; Monika Sharma
Journal:  Trop Parasitol       Date:  2012-01

6.  Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies.

Authors:  Linda E Kelemen; Fergus J Couch; Shahana Ahmed; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Zachary S Fredericksen; Robert A Vierkant; V Shane Pankratz; Ellen L Goode; Christopher G Scott; David N Rider; Xianshu Wang; James R Cerhan; Celine M Vachon
Journal:  Breast Cancer Res       Date:  2008-11-26       Impact factor: 6.466

Review 7.  Automated analytical microarrays: a critical review.

Authors:  Michael Seidel; Reinhard Niessner
Journal:  Anal Bioanal Chem       Date:  2008-05-27       Impact factor: 4.142

  7 in total

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