BACKGROUND: The diagnosis of idiopathic central serous retinopathy (CSR) is usually based on biomicroscopy and fluorescein angiography (FA). The optical coherence tomography (OCT) ophthalmoscope produces en face OCT scans (OCT C-scans) and provides additional information not readily available by conventional imaging techniques. The authors describe the characteristic features observed in patients with a clinical diagnosis of CSR using the OCT ophthalmoscope. METHODS: 38 eyes with a clinical diagnosis of CSR, seen at the Academic Medical Centre (Amsterdam, Netherlands) and the New York Eye and Ear Infirmary (New York, USA) between August 2002 and March 2004, were evaluated with standard digital FA and scanned with the OCT ophthalmoscope. RESULTS: Nine of 38 eyes had no serous neurosensory detachment (inactive CSR) when scanned with the OCT ophthalmoscope. Characteristics for active CSR (n=29) were large neurosensory detachment (23/29), subretinal hyper-reflective depoits (20/29), and pigment epithelial detachment (15/29). One third of the patients, either active or inactive, had multiple small pigment epithelial detachments located both within and outside the neurosensory detachment. CONCLUSION: The OCT ophthalmoscope provides complementary morphological information on patients with CSR. The presence of more diffuse retinal pigment epithelium (RPE) changes lends further support to the concept that CSR is a diffuse rather than localised RPE anomaly.
BACKGROUND: The diagnosis of idiopathic central serous retinopathy (CSR) is usually based on biomicroscopy and fluorescein angiography (FA). The optical coherence tomography (OCT) ophthalmoscope produces en face OCT scans (OCT C-scans) and provides additional information not readily available by conventional imaging techniques. The authors describe the characteristic features observed in patients with a clinical diagnosis of CSR using the OCT ophthalmoscope. METHODS: 38 eyes with a clinical diagnosis of CSR, seen at the Academic Medical Centre (Amsterdam, Netherlands) and the New York Eye and Ear Infirmary (New York, USA) between August 2002 and March 2004, were evaluated with standard digital FA and scanned with the OCT ophthalmoscope. RESULTS: Nine of 38 eyes had no serous neurosensory detachment (inactive CSR) when scanned with the OCT ophthalmoscope. Characteristics for active CSR (n=29) were large neurosensory detachment (23/29), subretinal hyper-reflective depoits (20/29), and pigment epithelial detachment (15/29). One third of the patients, either active or inactive, had multiple small pigment epithelial detachments located both within and outside the neurosensory detachment. CONCLUSION: The OCT ophthalmoscope provides complementary morphological information on patients with CSR. The presence of more diffuse retinal pigment epithelium (RPE) changes lends further support to the concept that CSR is a diffuse rather than localised RPE anomaly.
Authors: Adrian Gh Podoleanu; George M Dobre; Radu G Cucu; Richard Rosen; Patricia Garcia; Juan Nieto; Daniel Will; Ronald Gentile; Thomas Muldoon; Joseph Walsh; Lawrence A Yannuzzi; Yale Fisher; Dennis Orlock; Rishard Weitz; John A Rogers; Shane Dunne; Aaron Boxer Journal: J Biomed Opt Date: 2004 Jan-Feb Impact factor: 3.170
Authors: M R Hee; C A Puliafito; C Wong; E Reichel; J S Duker; J S Schuman; E A Swanson; J G Fujimoto Journal: Am J Ophthalmol Date: 1995-07 Impact factor: 5.258
Authors: Rogério A Costa; Luciana Scapucin; Nilva S Moraes; Daniela Calucci; Luiz A Melo; José A Cardillo; Michel E Farah Journal: Curr Eye Res Date: 2002-11 Impact factor: 2.424
Authors: Mirjam E J van Velthoven; Koos de Vos; Frank D Verbraak; Chris W Pool; Marc D de Smet Journal: BMC Ophthalmol Date: 2005-06-13 Impact factor: 2.209
Authors: Daniela Ferrara; Kathrin J Mohler; Nadia Waheed; Mehreen Adhi; Jonathan J Liu; Ireneusz Grulkowski; Martin F Kraus; Caroline Baumal; Joachim Hornegger; James G Fujimoto; Jay S Duker Journal: Ophthalmology Date: 2013-11-26 Impact factor: 12.079