| Literature DB >> 16231422 |
Lothar Hennighausen1, Gertraud W Robinson.
Abstract
Unique developmental features during puberty, pregnancy, lactation and post-lactation make the mammary gland a prime object to explore genetic circuits that control the specification, proliferation, differentiation, survival and death of cells. Steroids and simple peptide hormones initiate and carry out complex developmental programmes, and reverse genetics has been used to define the underlying mechanistic connections.Entities:
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Year: 2005 PMID: 16231422 DOI: 10.1038/nrm1714
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN: 1471-0072 Impact factor: 94.444