| Literature DB >> 16230530 |
Abstract
This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the post-genome era, but in many ways are leading the way to the promise of a "systems-level" understanding of complex processes such as notochord formation, neurogenesis, and even behavior.Mesh:
Year: 2005 PMID: 16230530 PMCID: PMC1257394 DOI: 10.1101/gad.1365805
Source DB: PubMed Journal: Genes Dev ISSN: 0890-9369 Impact factor: 11.361