| Literature DB >> 16229968 |
A M S Rodrigues1, J E de Paula, F Roblot, A Fournet, L S Espíndola.
Abstract
The larvicidal activity against Aedes aegypti larvae of a stem wood hexane extract of Cybistax antisyphilitica was evaluated. Bioassay-guided fractionation of the crude extract, monitored by larvicidal assay, led to the isolation of a natural quinone identified as 2-hydroxy-3-(3-methyl-2-butenyl)-1.4-naphthoquinone (lapachol). This compound was quite potent against A. aegypti larvae (LC50 26.3 microg/ml).Entities:
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Year: 2005 PMID: 16229968 DOI: 10.1016/j.fitote.2005.08.015
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882