Literature DB >> 16229901

Novel prenyltransferase enzymes as a tool for flavonoid prenylation.

Bruno Botta1, Giuliano Delle Monache, Pilar Menendez, Alberto Boffi.   

Abstract

The recent identification of genes encoding a novel family of soluble aromatic prenyltransferases from Streptomyces species and the structural characterization of one of these proteins are challenging discoveries in the biochemistry of natural compounds. In addition to their notable physiological role in the biosynthesis of aminocoumarin antibiotics, these enzymes represent an advanced tool for exploring novel isoprenoid substitutions in aromatic compounds and are expected to foster the emerging pharmacological applications of prenylated flavonoids.

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Year:  2005        PMID： 16229901     DOI： 10.1016/j.tips.2005.09.012

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  20 in total

1.  Molecular characterization and phylogenetic analysis of two novel regio-specific flavonoid prenyltransferases from Morus alba and Cudrania tricuspidata.

Authors:  Ruishan Wang; Ridao Chen; Jianhua Li; Xiao Liu; Kebo Xie; Dawei Chen; Yunze Yin; Xiaoyu Tao; Dan Xie; Jianhua Zou; Lin Yang; Jungui Dai
Journal:  J Biol Chem       Date:  2014-10-31       Impact factor: 5.157

Review 2.  Structural and functional dissection of aminocoumarin antibiotic biosynthesis: a review.

Authors:  David M Lawson; Clare E M Stevenson
Journal:  J Struct Funct Genomics       Date:  2012-05-27

3.  Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases.

Authors:  Yit-Heng Chooi; Peng Wang; Jinxu Fang; Yanran Li; Katherine Wu; Pin Wang; Yi Tang
Journal:  J Am Chem Soc       Date:  2012-05-25       Impact factor: 15.419

4.  Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593.

Authors:  Shunji Takahashi; Hiroshi Takagi; Atsushi Toyoda; Masakazu Uramoto; Toshihiko Nogawa; Masashi Ueki; Yoshiyuki Sakaki; Hiroyuki Osada
Journal:  J Bacteriol       Date:  2010-03-26       Impact factor: 3.490

5.  Positive selection drives neofunctionalization of the UbiA prenyltransferase gene family.

Authors:  Jiao Wang; Shanshan Chu; Ying Zhu; Hao Cheng; Deyue Yu
Journal:  Plant Mol Biol       Date:  2015-01-21       Impact factor: 4.076

6.  Palladium-catalyzed completely linear-selective Negishi cross-coupling of allylzinc halides with aryl and vinyl electrophiles.

Authors:  Yang Yang; Thomas J L Mustard; Paul Ha-Yeon Cheong; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-08       Impact factor: 15.336

7.  A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction.

Authors:  Elisa Haug-Schifferdecker; Deniz Arican; Reinhard Brückner; Lutz Heide
Journal:  J Biol Chem       Date:  2010-03-29       Impact factor: 5.157

8.  Biotransformation of menadione to its prenylated derivative MK-3 using recombinant Pichia pastoris.

Authors:  Zhemin Li; Genhai Zhao; Hui Liu; Yugang Guo; Hefang Wu; Xiaowen Sun; Xihua Wu; Zhiming Zheng
Journal:  J Ind Microbiol Biotechnol       Date:  2017-03-03       Impact factor: 3.346

9.  Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD.

Authors:  Benjamin W Roose; David W Christianson
Journal:  Biochemistry       Date:  2019-07-15       Impact factor: 3.162

Review 10.  The ABBA family of aromatic prenyltransferases: broadening natural product diversity.

Authors:  M Tello; T Kuzuyama; L Heide; J P Noel; S B Richard
Journal:  Cell Mol Life Sci       Date:  2008-05       Impact factor: 9.261
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