Literature DB >> 16228650

On the chemical nature and origin of teleonomy.

Addy Pross1.   

Abstract

The physico-chemical characterization of a teleonomic event and the nature of the physico-chemical process by which teleonomic systems could emerge from non-teleonomic systems are addressed in this paper. It is proposed that teleonomic events are those whose primary directive is discerned to be non-thermodynamic, while regular (non-teleonomic) events are those whose primary directive is the traditional thermodynamic one. For the archetypal teleonomic event, cell multiplication, the non-thermodynamic directive can be identified as being a kinetic directive. It is concluded, therefore, that the process of emergence, whereby non-teleonomic replicating chemical systems were transformed into teleonomic ones, involved a switch in the primacy of thermodynamic and kinetic directives. It is proposed that the step where that transformation took place was the one in which some pre-metabolic replicating system acquired an energy-gathering capability, thereby becoming metabolic. Such a transformation was itself kinetically directed given that metabolic replicators tend to be kinetically more stable than non-metabolic ones. The analysis builds on our previous work that considers living systems to be a kinetic state of matter as opposed to the traditional thermodynamic states that dominate the inanimate world.

Mesh:

Year:  2005        PMID: 16228650     DOI: 10.1007/s11084-005-2045-9

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN: 0169-6149            Impact factor:   1.950


  10 in total

1.  Unnatural selection in chemical systems.

Authors:  L E Orgel
Journal:  Acc Chem Res       Date:  1995-03       Impact factor: 22.384

2.  The driving force for life's emergence: kinetic and thermodynamic considerations.

Authors:  Addy Pross
Journal:  J Theor Biol       Date:  2003-02-07       Impact factor: 2.691

3.  Causation and the origin of life. Metabolism or replication first?

Authors:  Addy Pross
Journal:  Orig Life Evol Biosph       Date:  2004-06       Impact factor: 1.950

Review 4.  On the emergence of biological complexity: life as a kinetic state of matter.

Authors:  Addy Pross
Journal:  Orig Life Evol Biosph       Date:  2005-04       Impact factor: 1.950

Review 5.  Autocatalytic networks: the transition from molecular self-replication to molecular ecosystems.

Authors:  D H Lee; K Severin; M R Ghadiri
Journal:  Curr Opin Chem Biol       Date:  1997-12       Impact factor: 8.822

6.  Selective amplification by auto- and cross-catalysis in a replicating peptide system.

Authors:  S Yao; I Ghosh; R Zutshi; J Chmielewski
Journal:  Nature       Date:  1998-12-03       Impact factor: 49.962

7.  Emergence of symbiosis in peptide self-replication through a hypercyclic network.

Authors:  D H Lee; K Severin; Y Yokobayashi; M R Ghadiri
Journal:  Nature       Date:  1997-12-11       Impact factor: 49.962

Review 8.  Selforganization of matter and the evolution of biological macromolecules.

Authors:  M Eigen
Journal:  Naturwissenschaften       Date:  1971-10

9.  Self-replication of complementary nucleotide-based oligomers.

Authors:  D Sievers; G von Kiedrowski
Journal:  Nature       Date:  1994-05-19       Impact factor: 49.962

10.  Chemical selection, diversity, teleonomy and the second law of thermodynamics. Reflections on Eigen's theory of self-organization of matter.

Authors:  S Lifson
Journal:  Biophys Chem       Date:  1987-05-09       Impact factor: 2.352

  10 in total
  1 in total

1.  Life's Order, Complexity, Organization, and Its Thermodynamic-Holistic Imperatives.

Authors:  Richard Egel
Journal:  Life (Basel)       Date:  2012-11-13
  1 in total

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