Literature DB >> 162285

A colorimetric assay of lysogenic induction designed for screening potential carcinogenic and carcinostatic agents.

R K Elespuru, M B Yarmolinsky.   

Abstract

Simple, rapid colorimetric tests for lysogenic induction (the derepression of a latent bacterial virus) are described. A quantitative test and a more rapid semiquantitative test are based on the assay of the beta-galactosidase synthesized from lacZ gene fused to an operon under lambda repressor control. These biochemical "inductests" are suitable for screening programs designed to detect agents that damage DNA and that are of potential interest in carcinogenesis and cancer chemotherapy.

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Year:  1979        PMID： 162285     DOI： 10.1002/em.2860010113

Source DB:  PubMed          Journal:  Environ Mutagen        ISSN： 0192-2521


  19 in total

1.  Protective role for H-NS protein in IS1 transposition.

Authors:  Claudine Rouquette; Marie-Claude Serre; David Lane
Journal:  J Bacteriol       Date:  2004-04       Impact factor: 3.490

2.  Participation of the lytic replicon in bacteriophage P1 plasmid maintenance.

Authors:  M B Yarmolinsky; E B Hansen; S Jafri; D K Chattoraj
Journal:  J Bacteriol       Date:  1989-09       Impact factor: 3.490

3.  Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides.

Authors:  S W Mamber; K W Brookshire; S Forenza
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

4.  SOS induction by thermosensitive replication mutants of miniF plasmid.

Authors:  S Sommer; A Bailone; R Devoret
Journal:  Mol Gen Genet       Date:  1985

5.  Effect of an umuC mutation on phage lambda induction.

Authors:  J Jenek; P Quillardet; M Hofnung
Journal:  Mol Gen Genet       Date:  1985

6.  Light-dependent activity of the antitumor antibiotics ravidomycin and desacetylravidomycin.

Authors:  M Greenstein; T Monji; R Yeung; W M Maiese; R J White
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

7.  Intrasubunit and intersubunit interactions controlling assembly of active synaptic complexes during Hin-catalyzed DNA recombination.

Authors:  John K Heiss; Erin R Sanders; Reid C Johnson
Journal:  J Mol Biol       Date:  2011-06-25       Impact factor: 5.469

8.  Mutagenesis of the IS1 transposase: importance of a His-Arg-Tyr triad for activity.

Authors:  M C Serre; C Turlan; M Bortolin; M Chandler
Journal:  J Bacteriol       Date:  1995-09       Impact factor: 3.490

9.  Is the IS1 transposase, InsAB', the only IS1-encoded protein required for efficient transposition?

Authors:  J M Escoubas; D Lane; M Chandler
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490

10.  Anti-Candida and mode of action of two newly synthesized polymers: a modified poly (methylmethacrylate-co-vinylbenzoylchloride) and a modified linear poly (chloroethylvinylether-co-vinylbenzoylchloride) with special reference to Candida albicans and Candida tropicalis.

Authors:  Yehia A G Mahmoud; Magda M Aly
Journal:  Mycopathologia       Date:  2004-02       Impact factor: 2.574
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