Literature DB >> 16228277

Effects of a combinations of emodepside and praziquantel on parasites of reptiles and rodents.

H Mehlhorn1, G Schmahl2, M Frese2, I Mevissen2, A Harder3, K Krieger3.   

Abstract

A new combination of two anthelmintic compounds containing emodepside and praziquantel (Profender, Bayer AG, Levekusen, Germany) was tested in pet rodents and reptiles. Topical application of the two compounds led to the quick disappearance of nematodes and cestodes from a broad spectrum of hosts including mice, jirds, snakes, anole lizards, turtles, monitor lizards, etc. In reptiles the dosage had to be increased, since the thick outer layer of the epidermis hinders the penetration of the compounds. In animals with an extremely thick epidermis (e.g. monitor lizards, leguans) the new product was applied under the armpits.

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Year:  2005        PMID: 16228277     DOI: 10.1007/s00436-005-1446-z

Source DB:  PubMed          Journal:  Parasitol Res        ISSN: 0932-0113            Impact factor:   2.289


  6 in total

1.  In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis.

Authors:  Daniel Kulke; Jürgen Krücken; Janina Demeler; Achim Harder; Heinz Mehlhorn; Georg von Samson-Himmelstjerna
Journal:  Parasitol Res       Date:  2012-10-02       Impact factor: 2.289

Review 2.  Antiparasitic treatment of cerebral cysticercosis: lessons and experiences from China.

Authors:  Wei Wu; Fengju Jia; Wei Wang; Yixin Huang; Yong Huang
Journal:  Parasitol Res       Date:  2013-05-22       Impact factor: 2.289

3.  Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside.

Authors:  Daniel Kulke; Georg von Samson-Himmelstjerna; Sandra M Miltsch; Adrian J Wolstenholme; Aaron R Jex; Robin B Gasser; Cristina Ballesteros; Timothy G Geary; Jennifer Keiser; Simon Townson; Achim Harder; Jürgen Krücken
Journal:  PLoS Negl Trop Dis       Date:  2014-12-18

Review 4.  Potential of Traditional Knowledge of Plants in the Management of Arthropods in Livestock Industry with Focus on (Acari) Ticks.

Authors:  Wycliffe Wanzala
Journal:  Evid Based Complement Alternat Med       Date:  2017-07-17       Impact factor: 2.629

Review 5.  Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

Authors:  Jürgen Krücken; Lindy Holden-Dye; Jennifer Keiser; Roger K Prichard; Simon Townson; Benjamin L Makepeace; Marc P Hübner; Steffen R Hahnel; Ivan Scandale; Achim Harder; Daniel Kulke
Journal:  PLoS Pathog       Date:  2021-07-22       Impact factor: 6.823

6.  Efficacy of cyclooctadepsipeptides and aminophenylamidines against larval, immature and mature adult stages of a parasitologically characterized trichurosis model in mice.

Authors:  Daniel Kulke; Jürgen Krücken; Achim Harder; Georg von Samson-Himmelstjerna
Journal:  PLoS Negl Trop Dis       Date:  2014-02-20
  6 in total

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