Literature DB >> 16228009

Avian flu: isolation of drug-resistant H5N1 virus.

Q Mai Le1, Maki Kiso, Kazuhiko Someya, Yuko T Sakai, T Hien Nguyen, Khan H L Nguyen, N Dinh Pham, Ha H Ngyen, Shinya Yamada, Yukiko Muramoto, Taisuke Horimoto, Ayato Takada, Hideo Goto, Takashi Suzuki, Yasuo Suzuki, Yoshihiro Kawaoka.   

Abstract

The persistence of H5N1 avian influenza viruses in many Asian countries and their ability to cause fatal infections in humans have raised serious concerns about a global flu pandemic. Here we report the isolation of an H5N1 virus from a Vietnamese girl that is resistant to the drug oseltamivir, which is an inhibitor of the viral enzyme neuraminidase and is currently used for protection against and treatment of influenza. Further investigation is necessary to determine the prevalence of oseltamivir-resistant H5N1 viruses among patients treated with this drug.

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Year:  2005        PMID: 16228009     DOI: 10.1038/4371108a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  268 in total

1.  Receptor tyrosine kinase inhibitors that block replication of influenza a and other viruses.

Authors:  Naveen Kumar; Nishi R Sharma; Hinh Ly; Tristram G Parslow; Yuying Liang
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

2.  Enhanced growth of influenza vaccine seed viruses in vero cells mediated by broadening the optimal pH range for virus membrane fusion.

Authors:  Shin Murakami; Taisuke Horimoto; Mutsumi Ito; Ryo Takano; Hiroaki Katsura; Masayuki Shimojima; Yoshihiro Kawaoka
Journal:  J Virol       Date:  2011-11-16       Impact factor: 5.103

Review 3.  Novel vaccines against influenza viruses.

Authors:  S M Kang; J M Song; R W Compans
Journal:  Virus Res       Date:  2011-10-01       Impact factor: 3.303

4.  Influenza Virus.

Authors: 
Journal:  Transfus Med Hemother       Date:  2009       Impact factor: 3.747

Review 5.  Influenza: the once and future pandemic.

Authors:  Jeffery K Taubenberger; David M Morens
Journal:  Public Health Rep       Date:  2010-04       Impact factor: 2.792

6.  Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles.

Authors:  Jae-Min Song; Jaber Hossain; Dae-Goon Yoo; Aleksandr S Lipatov; C Todd Davis; Fu-Shi Quan; Li-Mei Chen; Robert J Hogan; Ruben O Donis; Richard W Compans; Sang-Moo Kang
Journal:  Virology       Date:  2010-06-26       Impact factor: 3.616

7.  Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors.

Authors:  Andrés Pizzorno; Xavier Bouhy; Yacine Abed; Guy Boivin
Journal:  J Infect Dis       Date:  2011-01-01       Impact factor: 5.226

8.  Analysis of oseltamivir resistance substitutions in influenza virus glycoprotein neuraminidase using a lentivirus-based surrogate assay system.

Authors:  Jennifer Tisoncik-Go; Katie S Cordero; Lijun Rong
Journal:  Virol Sin       Date:  2013-02-06       Impact factor: 4.327

9.  Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.

Authors:  Sanmitra Barman; Lei You; Ran Chen; Vlad Codrea; Grace Kago; Ramakrishna Edupuganti; Jon Robertus; Robert M Krug; Eric V Anslyn
Journal:  Eur J Med Chem       Date:  2013-11-07       Impact factor: 6.514

10.  A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin.

Authors:  Xueyong Zhu; Yong-Hui Guo; Tao Jiang; Ya-Di Wang; Kwok-Hung Chan; Xiao-Feng Li; Wenli Yu; Ryan McBride; James C Paulson; Kwok-Yung Yuen; Cheng-Feng Qin; Xiao-Yan Che; Ian A Wilson
Journal:  J Virol       Date:  2013-09-18       Impact factor: 5.103

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