Literature DB >> 16226538

Visual loss as a first sign of adult-type chronic myeloid leukemia in a child.

Günther Rudolph1, Christos Haritoglou, Irene Schmid, Friedericke Hochhaus, Anselm Kampik.   

Abstract

PURPOSE: To report the unusual case of retinal leukemic infiltration in a child with adult-type chronic myelocytic leukemia.
DESIGN: Interventional case report.
METHODS: Complete ophthalmologic examination, including visual acuity measurement and funduscopy. The diagnosis was established by blood cell counts and confirmed by a positive Philadelphia-chromosome translocation (t [9,22]). Treatment consisted of hydroxyurea and stem-cell transplantation.
RESULTS: After therapy, complete regression of the retinal lesion was observed with full recovery of visual acuity.
CONCLUSION: This case underlines the importance of interdisciplinary cooperation between ophthalmologists and pediatric oncologists in the diagnosis and treatment of this disease.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16226538     DOI: 10.1016/j.ajo.2005.04.036

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  2 in total

1.  Chronic myeloid leukemia presenting with visual and auditory impairment in an adolescent: an insight to management strategies.

Authors:  Muge Gokce; Sule Unal; Benan Bayrakçı; Murat Tuncer
Journal:  Indian J Hematol Blood Transfus       Date:  2010-10-01       Impact factor: 0.900

2.  [Sudden bilateral decreased vision in a 14-year-old boy].

Authors:  S Marx; A Scheuerle; R Khoramnia; T Tandogan; D Kaiser; G U Auffarth; S Sel
Journal:  Ophthalmologe       Date:  2017-08       Impact factor: 1.059

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.