Literature DB >> 16226500

Pathogen recognition: TLRs throw us a curve.

Peter Kirk1, J Fernando Bazan.   

Abstract

Toll-like receptors (TLRs) are the archetypal pattern recognition receptors (PRRs) envisioned by as innate sensors of pathogen attack and host triggers of an adaptive immune response. Two recent papers (Choe et al., 2005; Bell et al., 2005) reveal the distinctive architecture of a TLR sensor domain and hint at how this structural design facilitates the recognition of a wide array of pathogen molecules.

Mesh：

Substances：

Year:  2005        PMID： 16226500     DOI： 10.1016/j.immuni.2005.09.008

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  9 in total

1.  Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1beta.

Authors:  Aneta Dobierzewska; Natalia V Giltiay; Sathish Sabapathi; Alexander A Karakashian; Mariana N Nikolova-Karakashian
Journal:  J Biol Chem       Date:  2011-06-27       Impact factor: 5.157

2.  Blocking TIR Domain Interactions in TLR9 Signaling.

Authors:  Artur Javmen; Henryk Szmacinski; Joseph R Lakowicz; Vladimir Y Toshchakov
Journal:  J Immunol       Date:  2018-06-18       Impact factor: 5.422

3.  Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1.

Authors:  Atsushi Iwai; Takuya Shiozaki; Taro Kawai; Shizuo Akira; Yoshihiro Kawaoka; Ayato Takada; Hiroshi Kida; Tadaaki Miyazaki
Journal:  J Biol Chem       Date:  2010-08-10       Impact factor: 5.157

4.  Cyprinid-specific duplicated membrane TLR5 senses dsRNA as functional homodimeric receptors.

Authors:  Zhiwei Liao; Chunrong Yang; Rui Jiang; Wentao Zhu; Yongan Zhang; Jianguo Su
Journal:  EMBO Rep       Date:  2022-06-09       Impact factor: 9.071

5.  Toll-like receptors and myocardial ischemia/reperfusion, inflammation, and injury.

Authors:  David J Kaczorowski; Atsunori Nakao; Kenneth R McCurry; Timothy R Billiar
Journal:  Curr Cardiol Rev       Date:  2009-08

6.  Construction of a large scale integrated map of macrophage pathogen recognition and effector systems.

Authors:  Sobia Raza; Neil McDerment; Paul A Lacaze; Kevin Robertson; Steven Watterson; Ying Chen; Michael Chisholm; George Eleftheriadis; Stephanie Monk; Maire O'Sullivan; Arran Turnbull; Douglas Roy; Athanasios Theocharidis; Peter Ghazal; Tom C Freeman
Journal:  BMC Syst Biol       Date:  2010-05-14

7.  Tumor necrosis factor-alpha (TNF-alpha) regulates Toll-like receptor 2 (TLR2) expression in microglia.

Authors:  Mohsin Md Syed; Nirmal K Phulwani; Tammy Kielian
Journal:  J Neurochem       Date:  2007-11       Impact factor: 5.372

Review 8.  Single Domain Antibody application in bacterial infection diagnosis and neutralization.

Authors:  Qian Qin; Hao Liu; Wenbo He; Yucheng Guo; Jiaxin Zhang; Junjun She; Fang Zheng; Sicai Zhang; Serge Muyldermans; Yurong Wen
Journal:  Front Immunol       Date:  2022-09-29       Impact factor: 8.786

9.  Lipopolysaccharide From E. coli Increases Glutamate-Induced Disturbances of Calcium Homeostasis, the Functional State of Mitochondria, and the Death of Cultured Cortical Neurons.

Authors:  Zanda Bakaeva; Natalia Lizunova; Ivan Tarzhanov; Dmitrii Boyarkin; Svetlana Petrichuk; Vsevolod Pinelis; Andrey Fisenko; Alexander Tuzikov; Rinat Sharipov; Alexander Surin
Journal:  Front Mol Neurosci       Date:  2022-01-05       Impact factor: 5.639
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.