Literature DB >> 16226154

The relationship between performance on the standardised field sobriety tests, driving performance and the level of Delta9-tetrahydrocannabinol (THC) in blood.

K Papafotiou1, J D Carter, C Stough.   

Abstract

The consumption of Delta9-tetrahydrocannabinol (THC) as cannabis has been shown to result in impaired and culpable driving. Testing drivers for the presence of THC in blood is problematic as THC and its metabolites may remain in the blood for several days following its consumption, even though the drug may no longer have an influence on driving performance. In the present study, the aim was to assess whether performance on the standardised field sobriety tests (SFSTs) provides a sensitive measure of impaired driving behaviour following the consumption of THC. In a repeated measures design, 40 participants consumed cigarettes that contained either 0% THC (placebo), 1.74% THC (low dose) or 2.93% THC (high dose). For each condition, after smoking a cigarette, participants performed the SFSTs on three occasions (5, 55 and 105 min after the smoking procedure had been completed) as well as a simulated driving test on two occasions (30 and 80 min after the smoking procedure had been completed). The results revealed that driving performance was not significantly impaired 30 min after the consumption of THC but was significantly impaired 80 min after the consumption of THC in both the low and high dose conditions. The percentage of participants whose driving performance was correctly classified as either impaired or not impaired based on the SFSTs ranged between 65.8 and 76.3%, across the two THC conditions. The results suggest that performance on the SFSTs provides a moderate predictor of driving impairment following the consumption of THC and as such, the SFSTs may provide an appropriate screening tool for authorities that wish to assess the driving capabilities of individuals suspected of being under the influence of a drug other than alcohol.

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Year:  2005        PMID: 16226154     DOI: 10.1016/j.forsciint.2004.11.009

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  18 in total

1.  Continuity of drunk and drugged driving behaviors four years post-college.

Authors:  Kimberly M Caldeira; Amelia M Arria; Hannah K Allen; Brittany A Bugbee; Kathryn B Vincent; Kevin E O'Grady
Journal:  Drug Alcohol Depend       Date:  2017-09-18       Impact factor: 4.492

2.  Cannabis and Canada's children and youth.

Authors:  Christina N Grant; Richard E Bélanger
Journal:  Paediatr Child Health       Date:  2017-05-03       Impact factor: 2.253

3.  Postmortem redistribution of Δ9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC), and 11-nor-9-carboxy-THC (THCCOOH).

Authors:  Michael G Holland; David M Schwope; Robert Stoppacher; Shane B Gillen; Marilyn A Huestis
Journal:  Forensic Sci Int       Date:  2011-07-20       Impact factor: 2.395

4.  Substance-related traffic-risk behaviors among college students.

Authors:  Amelia M Arria; Kimberly M Caldeira; Kathryn B Vincent; Laura M Garnier-Dykstra; Kevin E O'Grady
Journal:  Drug Alcohol Depend       Date:  2011-05-20       Impact factor: 4.492

5.  MDMA and methamphetamine: some paradoxical negative and positive mood changes in an acute dose laboratory study.

Authors:  Andrew C Parrott; Amy Gibbs; Andrew B Scholey; Rebecca King; Katherine Owens; Phil Swann; Ed Ogden; Con Stough
Journal:  Psychopharmacology (Berl)       Date:  2011-02-12       Impact factor: 4.530

6.  Acute Pharmacokinetic Profile of Smoked and Vaporized Cannabis in Human Blood and Oral Fluid.

Authors:  Tory R Spindle; Edward J Cone; Nicolas J Schlienz; John M Mitchell; George E Bigelow; Ronald Flegel; Eugene Hayes; Ryan Vandrey
Journal:  J Anal Toxicol       Date:  2019-05-01       Impact factor: 3.367

Review 7.  Cannabis effects on driving skills.

Authors:  Rebecca L Hartman; Marilyn A Huestis
Journal:  Clin Chem       Date:  2012-12-07       Impact factor: 8.327

8.  Effects of three therapeutic doses of codeine/paracetamol on driving performance, a psychomotor vigilance test, and subjective feelings.

Authors:  Jean-Noël Amato; Sullivan Marie; Véronique Lelong-Boulouard; Magalie Paillet-Loilier; Catherine Berthelon; Antoine Coquerel; Pierre Denise; Marie-Laure Bocca
Journal:  Psychopharmacology (Berl)       Date:  2013-03-09       Impact factor: 4.530

9.  Implications of plasma Delta9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers.

Authors:  Erin L Karschner; Eugene W Schwilke; Ross H Lowe; W David Darwin; Ronald I Herning; Jean Lud Cadet; Marilyn A Huestis
Journal:  J Anal Toxicol       Date:  2009-10       Impact factor: 3.367

Review 10.  The effect of cannabis compared with alcohol on driving.

Authors:  R Andrew Sewell; James Poling; Mehmet Sofuoglu
Journal:  Am J Addict       Date:  2009 May-Jun
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