Literature DB >> 16224597

Glycosaminoglycans of the vertebral body growth plate in patients with idiopathic scoliosis.

T V Rusova1, V I Rykova, A V Korel, A M Zaidman, D S Tkachev.   

Abstract

The concentrations of keratan sulfates and unmodified keratan sulfates increased in the vertebral body growth plate in patients with idiopathic scoliosis. Sulfation and acetylation of total glycosaminoglycans decreased by 50 and 30%, respectively. These changes reflect the decrease in biological activity of molecules that modulate function of the growth plate.

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Year:  2005        PMID: 16224597     DOI: 10.1007/s10517-005-0394-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  2 in total

Review 1.  Adolescent idiopathic scoliosis: evidence for intrinsic factors driving aetiology and progression.

Authors:  Matthew M P Newton Ede; Simon W Jones
Journal:  Int Orthop       Date:  2016-03-10       Impact factor: 3.075

Review 2.  The metabolic basis of adolescent idiopathic scoliosis: 2011 report of the "metabolic" workgroup of the Fondation Yves Cotrel.

Authors:  Emre Acaroglu; Regis Bobe; Jocelyn Enouf; Ralph Marcucio; Florina Moldovan; Alain Moreau
Journal:  Eur Spine J       Date:  2012-03-09       Impact factor: 3.134

  2 in total

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