Literature DB >> 16223089

Rapid identification of vinca alkaloids by direct-injection electrospray ionisation tandem mass spectrometry and confirmation by high-performance liquid chromatography-mass spectrometry.

Hui Zhou1, Yuanpo Tai, Cuirong Sun, Yuanjiang Pan.   

Abstract

A simple and rapid method for the identification of Vinca alkaloids from a crude extract of Catharanthus roseus G. Don (Apocynaceae) by direct-injection electrospray ionisation (ESI) and tandem mass spectrometry (MS/MS) has been developed. The alkaloids vindoline, vindolidine, vincristine and vinblastine were evaluated in a commercial extract of C. roseus using this method. Catharanthine and its isomers 19S-vindolinine and vindolinine were detected in the commercial product by direct injection ESI/MS/MS and confirmed by preparation and by HPLC-ESI/MS. For the characterisation of different fragment fingerprints, ESI/MS/MS is a sensitive, rapid and convenient technique by which to identify some constituents in complex and mixed plant extracts.

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Year:  2005        PMID： 16223089     DOI： 10.1002/pca.852

Source DB:  PubMed          Journal:  Phytochem Anal        ISSN： 0958-0344            Impact factor:   3.373


  7 in total

1.  Direct Analysis of Aqueous Solutions and Untreated Biological Samples Using Nanoelectrospray Ionization Mass Spectrometry with Pipette Tip in Series with High-Ohmic Resistor as Ion Source.

Authors:  Matiur Rahman; Debo Wu; Konstantin Chingin
Journal:  J Am Soc Mass Spectrom       Date:  2019-03-04       Impact factor: 3.109

2.  "Self" and "non-self" in the control of phytoalexin biosynthesis: plant phospholipases A2 with alkaloid-specific molecular fingerprints.

Authors:  Michael Heinze; Wolfgang Brandt; Sylvestre Marillonnet; Werner Roos
Journal:  Plant Cell       Date:  2015-02-10       Impact factor: 11.277

3.  Enhancement of vincristine under in vitro culture of Catharanthus roseus supplemented with Alternaria sesami endophytic fungal extract as a biotic elicitor.

Authors:  Kanchan Birat; Tariq Omar Siddiqi; Showkat Rasool Mir; Junaid Aslan; Rakhi Bansal; Washim Khan; Rikeshwer Prasad Dewangan; Bibhu Prasad Panda
Journal:  Int Microbiol       Date:  2021-10-08       Impact factor: 2.479

4.  A simplified procedure for indole alkaloid extraction from Catharanthus roseus combined with a semi-synthetic production process for vinblastine.

Authors:  Arvind Verma; Into Laakso; Tuulikki Seppänen-Laakso; Aarre Huhtikangas; Marja-Liisa Riekkola
Journal:  Molecules       Date:  2007-07-05       Impact factor: 4.411

5.  Cell-specific localization of alkaloids in Catharanthus roseus stem tissue measured with Imaging MS and Single-cell MS.

Authors:  Kotaro Yamamoto; Katsutoshi Takahashi; Hajime Mizuno; Aya Anegawa; Kimitsune Ishizaki; Hidehiro Fukaki; Miwa Ohnishi; Mami Yamazaki; Tsutomu Masujima; Tetsuro Mimura
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-21       Impact factor: 11.205

6.  Simultaneous determination of secondary metabolites from Vinca rosea plant extractives by reverse phase high performance liquid chromatography.

Authors:  Mohammad Jamshed Ahmad Siddiqui; Zhari Ismail; Noor Hafizoh Saidan
Journal:  Pharmacogn Mag       Date:  2011-04       Impact factor: 1.085

7.  Isolation, purification and characterization of vinblastine and vincristine from endophytic fungus Fusarium oxysporum isolated from Catharanthus roseus.

Authors:  Ashutosh Kumar; Deepak Patil; Pattuparambil Ramanpillai Rajamohanan; Absar Ahmad
Journal:  PLoS One       Date:  2013-09-16       Impact factor: 3.240
  7 in total

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