Literature DB >> 16221951

Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis.

S T Engelter1, M Reichhart, L Sekoranja, D Georgiadis, A Baumann, B Weder, F Müller, R Lüthy, M Arnold, P Michel, H P Mattle, B Tettenborn, H J Hungerbühler, R W Baumgartner, R Sztajzel, J Bogousslavsky, P A Lyrer.   

Abstract

This databank-based, multicenter study compared all stroke patients with IV tissue plasminogen activator aged > or = 80 years (n = 38) and those < 80 years old (n = 287). Three-month mortality was higher in older patients. Favorable outcome (modified Rankin scale < or = 1) and intracranial hemorrhage (asymptomatic/symptomatic/fatal) were similarly frequent in both groups. Logistic regression showed that stroke severity, time to thrombolysis, glucose level, and history of coronary heart disease independently predicted outcome, whereas age did not.

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Year:  2005        PMID: 16221951     DOI: 10.1212/01.wnl.0000183702.04080.27

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  24 in total

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Journal:  Cerebrovasc Dis       Date:  2010-03-30       Impact factor: 2.762

Review 2.  [Thrombolysis for ischemic stroke: an update].

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Review 4.  Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients.

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Review 5.  [Difficult decisions in stroke therapy].

Authors:  M Endres; M Grond; W Hacke; M Ebinger; P D Schellinger; M Dichgans
Journal:  Nervenarzt       Date:  2011-08       Impact factor: 1.214

Review 6.  The effects of estrogen in ischemic stroke.

Authors:  Edward C Koellhoffer; Louise D McCullough
Journal:  Transl Stroke Res       Date:  2012-12-07       Impact factor: 6.829

Review 7.  Absolute and Relative Contraindications to IV rt-PA for Acute Ischemic Stroke.

Authors:  Jennifer E Fugate; Alejandro A Rabinstein
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Journal:  AJNR Am J Neuroradiol       Date:  2015-11-26       Impact factor: 3.825

9.  Effects of age on outcome in the SENTIS trial: better outcomes in elderly patients.

Authors:  Ronen R Leker; Carlos Molina; Kevin Cockroft; David S Liebeskind; Mauricio Concha; Ashfaq Shuaib; Peter Paul De Deyn; W Scott Burgin; Rishi Gupta; William Dillon; Hans-Christoph Diener
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Journal:  Int J Emerg Med       Date:  2008-05-31
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